Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System
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DOI: 10.1021/acscatal.0c00929
Abstract: The biocatalytic synthesis of amides from carboxylic acids and primary amines in aqueous media can be achieved using the ATP-dependent amide bond synthetase McbA, via an adenylate intermediate, using only 1.5 equiv of the amine… read more here.
Keywords: biocatalytic synthesis; mcba; bond synthetase; acid ... See more keywords