Impairment of the autophagy-lysosomal pathway and activation of pyroptosis in macular corneal dystrophy
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DOI: 10.1038/s41420-020-00320-z
Abstract: Macular corneal dystrophy (MCD) is ascribed to mutations in the carbohydrate sulfotransferase ( CHST6 ) gene affecting keratan sulfate (KS) hydrophilicity and causing non-sulfated KS to precipitate in keratocytes and the corneal stroma. We investigated… read more here.
Keywords: pathway activation; pyroptosis; macular corneal; corneal dystrophy ... See more keywords