Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D
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DOI: 10.1186/s12935-018-0534-y
Abstract: BackgroundThree-dimensional cultures of mammary epithelial cells allow for biologically-relevant studies of the development of the mammary gland in rodents and humans under normal and pathological conditions, like carcinogenesis. Under these conditions, mammotropic hormones play significant… read more here.
Keywords: 12a cell; cell phenotype; mcf 12a; 12a cells ... See more keywords
Comparison of the Toxicological Effects of Pesticides in Non-Tumorigenic MCF-12A and Tumorigenic MCF-7 Human Breast Cells
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DOI: 10.3390/ijerph19084453
Abstract: Humans are exposed to residues of organophosphate and neonicotinoid pesticides, commonly used in agriculture. Children are particularly vulnerable and, among possible adverse outcomes, the increased incidence of premature mammary gland development (thelarche) has raised concern.… read more here.
Keywords: non tumorigenic; mcf; toxicological effects; tumorigenic mcf ... See more keywords