C-Terminal modification of polytheonamide B uncouples its dual functions in MCF-7 cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc05915k
Abstract: Polytheonamide B (1) is an exceptionally large peptide that forms a transmembrane ion channel. The potent cytotoxicity of 1 against MCF-7 cancer cells originates from its two ion transport functions. Compound 1 depolarizes the plasma… read more here.
Keywords: modification polytheonamide; mcf cancer; cancer cells; terminal modification ... See more keywords
Differently sized drug-loaded mesoporous silica nanoparticles elicit differential gene expression in MCF-7 cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "Nanomedicine"
DOI: 10.2217/nnm-2020-0375
Abstract: Aim: This study investigates the effects of different sized unmodified and chemo-responsive mesoporous silica nanocarriers on MCF-7 cancer cells. Materials & methods: Unmodified and thiol-functionalized large and small-sized mesoporous MCM-41 silica nanoparticles prepared using templated… read more here.
Keywords: silica; mesoporous silica; silica nanoparticles; cancer cells ... See more keywords