Synthesis and Evaluation of Functionalized Aryl and Biaryl Isothiocyanates against Human MCF‐7 Cells
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200250
Abstract: Organic isothiocyanates (ITCs) are a class of anticancer agents which naturally result from the enzymatic degradation of glucosinolates produced by Brassica vegetables. Previous studies have demonstrated that the structure of an ITC impacts its potency… read more here.
Keywords: evaluation; human mcf; itc; mcf cells ... See more keywords
Atractylodin induces oxidative stress‐mediated apoptosis and autophagy in human breast cancer MCF‐7 cells through inhibition of the P13K/Akt/mTOR pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23081
Abstract: This study aimed to determine the apoptosis and autophagy‐inducing mechanism of atractylodin in human breast cancer MCF‐7 cells. The molecular mechanism of anticancer activity of atractylodin was confirmed by assessing the levels of reactive oxygen… read more here.
Keywords: mcf; apoptosis autophagy; breast cancer; human breast ... See more keywords
Inhibition of autophagic flux by the curcumin analog EF‐24 and its antiproliferative effect on MCF‐7 cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23307
Abstract: 5‐Bis[(2‐fluorophenyl)methylene]‐4‐piperidinone (EF‐24) is a curcumin analog, which was identified for its physiochemical stability and diverse pharmacological functions. In the present study, EF‐24 was added to the breast cancer cell line MCF‐7 and its cellular effects… read more here.
Keywords: mcf; autophagic flux; curcumin analog; mcf cells ... See more keywords
Oleuropein inhibits migration ability through suppression of epithelial‐mesenchymal transition and synergistically enhances doxorubicin‐mediated apoptosis in MCF‐7 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27586
Abstract: Distinct metastasis is one of the main causes of breast cancer (BC)‐related mortality and epithelial‐mesenchymal transition (EMT) is a primary step in metastasis dissemination. On the other hand, doxorubicin (DOX) is an effective chemotherapeutic agent… read more here.
Keywords: mcf cells; apoptosis; mcf; migration ability ... See more keywords
In vitro profiling of toxicity and endocrine disrupting effects of bisphenol analogues by employing MCF‐7 cells and two‐hybrid yeast bioassay
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DOI: 10.1002/tox.22234
Abstract: The potentially adverse health implications of bisphenol A (BPA) have led to increasing use of alternative bisphenols (BPs). However, little is known about the toxicity of alternative BPs. In this study, the cytotoxicity, genotoxicity, intracellular… read more here.
Keywords: disrupting effects; mcf cells; endocrine disrupting; hybrid yeast ... See more keywords
Reduced camptothecin sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di(2‐ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22694
Abstract: Di(2‐ethylhexyl)phthalate (DEHP) has been considered as an estrogen receptor alpha (ERα) agonist due to its ability to interact with ERα and promote the cell proliferation of ERα‐positive breast cancer cells. The impact of DEHP on… read more here.
Keywords: dehp; mcf cells; cancer cells; breast cancer ... See more keywords
Validation of Reference Genes for Silver Nanotoxicity Analysis in MCF-7 Cell Line
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cluster Science"
DOI: 10.1007/s10876-017-1313-y
Abstract: Following the increasing use of silver nanoparticles (AgNPs) and the growing exposure to these particles, nanotoxicity has become a general concern among researchers around the world. Although quantitative real time PCR (RT-qPCR) is the technique… read more here.
Keywords: reference; reference genes; mcf cells; analysis mcf ... See more keywords
The Comparative Cytotoxic Effects of Apis mellifera Crude Venom on MCF-7 Breast Cancer Cell Line in 2D and 3D Cell Cultures
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DOI: 10.1007/s10989-019-09979-0
Abstract: Bee venom (BV) has variety of properties, such as anti-inflammatory potential and anti-cancer activity.It has been shown that BV has cytotoxic effects on MCF-7 cells in 2D culture. Cell encapsulation is one of the three-dimensional… read more here.
Keywords: cytotoxic effects; mcf cells; venom; culture ... See more keywords
Expression profile analysis of a new testis-specifically expressed gene C17ORF64 and its association with cell apoptosis in MCF-7 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06191-6
Abstract: With the increasing incidence of male infertility, identification and investigation the functions of new genes related to spermatogenesis are effective avenues to elucidate the decline of testicular function. In this study, a new gene, C17ORF64… read more here.
Keywords: mcf cells; analysis; c17orf64; apoptosis mcf ... See more keywords
Estrogenic effects of phytoestrogens derived from Flemingia strobilifera in MCF-7 cells and immature rats
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DOI: 10.1007/s12272-018-1027-1
Abstract: Phytoestrogen (PE) has received considerable attention due to the physiological significance of its estrogenicity. Flemingia strobilifera (FS) has been used as a folk medicine in Asia for the treatment of inflammation, cancer, and infection; however,… read more here.
Keywords: mcf cells; fse compounds; mcf; estrogenic effects ... See more keywords
S-equol inhibits proliferation and promotes apoptosis of human breast cancer MCF-7 cells via regulating miR-10a-5p and PI3K/AKT pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108064
Abstract: S-equol is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora, which has strong anti-cancer activity. Based on this, the purpose of this study was to investigate the anti-breast… read more here.
Keywords: cancer; mir 10a; mcf cells; breast cancer ... See more keywords