Induction of apoptosis by chalepin through phosphatidylserine externalisations and DNA fragmentation in breast cancer cells (MCF7)
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.01.029
Abstract: Aims: Chalepin, a naturally occurring compound isolated from Ruta angustifolia have been shown to exert a promising anticancer activity through various mechanisms. Hence, the need to investigate the apoptotic inducing ability of chalepin in MCF7… read more here.
Keywords: chalepin; apoptosis; dna fragmentation; activity ... See more keywords
Synthesis of ring-A modified lupeol derivatives and their anti-proliferative activity: identification of potent lead active against MCF-7 breast cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2121827
Abstract: In continuation of our research program aimed at the development of new natural product-based anticancer agents, a series of lupeol derivatives (5a-5k and 6a-6i) were prepared with the introduction of aryl functionalities and amino acids… read more here.
Keywords: lupeol derivatives; activity; synthesis ring; mcf7 cells ... See more keywords
Abstract 4848: Effects of cinnamon extracted under acidic conditions on proliferation of MCF7 cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4848
Abstract: Recent evidence suggests that MCF7 cells utilize free fatty acids as a primary energy source by increasing lipase activity in neighboring adipocytes. Research in our lab suggests that lipase activity is increased by cinnamon extract… read more here.
Keywords: effects cinnamon; proliferation; proliferation mcf7; mcf7 cells ... See more keywords
ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.930227
Abstract: The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and function as ligand-inducible transcription factors. They are homologues and can form dimers with each other and bind to the same… read more here.
Keywords: cell; proliferation; homodimers cellular; migration ... See more keywords
3D Disease Modelling of Hard and Soft Cancer Using PHA-Based Scaffolds
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143549
Abstract: Simple Summary Tumour progression in vivo was able to be well mimicked in 3D culture by utilizing biodegradable 10 mm × 10 mm × 8 mm P(3HO-co-3HD) and P(3HB)-based 3D scaffolds with a pore size… read more here.
Keywords: pha scaffolds; mda 231; expression; mcf7 cells ... See more keywords
Investigating the Function of Human Jumping Translocation Breakpoint Protein (hJTB) and Its Interacting Partners through In-Solution Proteomics of MCF7 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238301
Abstract: Human jumping translocation breakpoint (hJTB) gene is located on chromosome 1q21 and is involved in unbalanced translocation in many types of cancer. JTB protein is ubiquitously present in normal cells but it is found to… read more here.
Keywords: translocation; jtb; mcf7 cells; solution ... See more keywords
Exposure to EGF and 17β‑estradiol irreversibly affects the proliferation and transformation of MCF7 cells but is not sufficient to promote tumor growth in a xenograft mouse model upon withdrawal of exposure.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2018.3737
Abstract: Epidermal growth factor (EGF) and estrogen are potent regulators of breast tumorigenesis. Their short‑term actions on human breast epithelial cells have been investigated extensively. However, the consequence of a long‑term exposure to EGF and estrogen… read more here.
Keywords: exposure egf; egf estradiol; exposure; proliferation ... See more keywords
Knockdown of ATG4A inhibits breast cancer progression and promotes tamoxifen chemosensitivity by suppressing autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12617
Abstract: Autophagy-related 4A (ATG4A) is an autophagy regulator. The current study investigated the role of ATG4A in the development of tamoxifen-resistant breast cancer. ATG4A expression was assessed in tumor and adjacent normal tissue obtained from The… read more here.
Keywords: cancer; expression; knockdown atg4a; mcf7 cells ... See more keywords