LMAN1–MCFD2 complex is a cargo receptor for the ER-Golgi transport of α1-antitrypsin
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DOI: 10.1042/bcj20220055
Abstract: α1-antitrypsin (AAT) is a serine protease inhibitor synthesized in hepatocytes and protects the lung from damage by neutrophil elastase. AAT gene mutations result in AAT deficiency (AATD), which leads to lung and liver diseases. The… read more here.
Keywords: lman1 mcfd2; mcfd2; secretion; aat ... See more keywords