Generation of faithful autochthonous mouse models of Mantle Cell Lymphoma
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DOI: 10.1182/blood-2025-1757
Abstract: Introduction: MantleCell Lymphoma (MCL) is characterized by the translocation t(11;14) resulting in overexpression of Cyclin D1. Other frequently observed alterations include SOX11 overexpression (90% of patients), and aberrations of ATM (42-56%) and TP53 (16-31%). Despite… read more here.
Keywords: mcl; cell; mcl like; lymphomagenesis ... See more keywords