Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions.
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DOI: 10.1016/j.celrep.2021.109440
Abstract: The minichromosome maintenance (MCM) helicase physically interacts with the recombination proteins Rad51 and Rad52 from yeast to human cells. We show, in Saccharomyces cerevisiae, that these interactions occur within a nuclease-insoluble scaffold enriched in replication/repair… read more here.
Keywords: replication fork; ssdna gap; mcm rad51; non recombinogenic ... See more keywords