Evaluation of the diagnostic and therapeutic roles of non-coding RNA and cell proliferation related gene association in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.04.054
Abstract: Micro RNA-34a-5p (miR-34a-5p) is an important molecule that can act as a modulator of tumor growth. It controls expression of a plenty of proteins controlling cell cycle, differentiation and apoptosis and opposing processes that favor… read more here.
Keywords: hcc; mir 34a; group; mcm2 ... See more keywords
Characterization and clinical validation of MCM2 and TOP2A monoclonal antibodies in the BD ProEx™ C assay: An immunoassay which detects aberrant S-phase induction in cervical tissue.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2017.01.002
Abstract: BACKGROUND The Papanicolaou (Pap) screen has been successful in reducing cervical cancer; but exhibits low sensitivity when detecting cervical dysplasia. Use of molecular biomarkers in Pap tests may improve diagnostic accuracy. DESIGN Monoclonal antibodies to… read more here.
Keywords: monoclonal antibodies; mcm2 top2a; cervical tissue; mcm2 ... See more keywords
Clinicopathologic significance of DNA replication licensing factors in head and neck diffuse large B-cell lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2021.10.018
Abstract: OBJECTIVE Diffuse large B-cell lymphoma (DLBCL) harbors defects in the proliferation pathway. We performed multiparameter analysis of proteins expressed during different cell cycle phases and correlated them with clinical parameters of head and neck DLBCLs.… read more here.
Keywords: cell lymphoma; mcm2; geminin; cell ... See more keywords
Comparative evaluation of immunohistochemical expression of MCM2 and Ki67 in oral epithelial dysplasia and oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_10_20
Abstract: Aim and Objectives: The aim and objective of the study were to evaluate the immunohistochemical expression of proliferative markers, Ki67, and MCM2 in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC), to compare… read more here.
Keywords: immunohistochemical expression; oral epithelial; expression; mcm2 ... See more keywords
Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.80917
Abstract: Mcm2, a subunit of the Mcm2-7 helicase best known for its role in DNA replication, contains a histone binding motif that facilitates the transfer of parental histones following DNA replication. Here we show that Mcm2… read more here.
Keywords: promotes stem; stem cell; mcm2 promotes; mcm2 ... See more keywords