MCM8 promotes gastric cancer progression through RPS15A and predicts poor prognosis
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DOI: 10.1002/cam4.7424
Abstract: Gastric cancer (GC) is the fourth leading cause of cancer‐related death worldwide. Minichromsome maintenance proteins family member 8 (MCM8) assists DNA repair and DNA replication. MCM8 exerts tumor promotor function in multiple digestive system tumors.… read more here.
Keywords: cancer; mcm8; promotes gastric; gastric cancer ... See more keywords
MCM8 is regulated by EGFR signaling and promotes the growth of glioma stem cells through its interaction with DNA-replication-initiating factors
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DOI: 10.1038/s41388-021-01888-1
Abstract: Mini-chromosome maintenance (MCM) proteins are critical components of DNA-replication-licensing factors. MCM8 is an MCM protein that exhibits oncogenic functions in several human malignancies. However, the role of MCM8 in glioblastomas (GBMs) has remained unclear. In… read more here.
Keywords: mcm8; regulated egfr; dna replication; expression ... See more keywords
AmNA‐Modified Antisense Oligonucleotide Targeting MCM8 as a Cancer‐Specific Chemosensitizer for Platinum Compounds
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DOI: 10.1111/cas.70024
Abstract: MCM8 and MCM9 participate in homologous recombination with long‐tract gene conversion to repair double‐strand breaks caused by replication stress, which is generally higher in cancer cells than in normal cells. MCM8 is highly expressed in… read more here.
Keywords: cancer; cancer cells; mcm8; antisense oligonucleotide ... See more keywords
MCM8 promotes lung cancer progression through upregulating DNAJC10
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DOI: 10.1111/jcmm.18488
Abstract: MCM8 is a helicase, which participates in DNA replication and tumorigenesis and is upregulated in many human cancers, including lung cancer (LC); however, the function of MCM8 in LC tumour progression is unclear. In this… read more here.
Keywords: lung cancer; mcm8; progression; mcm8 promotes ... See more keywords
Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo
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DOI: 10.1186/s12935-021-01948-2
Abstract: Background Bladder cancer is a frequently diagnosed urinary system tumor, whose mortality remains rising. Minichromosome maintenance eight homologous recombination repair factor (MCM8), a newly discovered MCM family member, has been shown to be required for… read more here.
Keywords: bladder cancer; mcm8; vitro; cancer ... See more keywords
Expression patterns of MCM8 in lung adenocarcinoma and its correlation with key biological processes
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Medical Research"
DOI: 10.1186/s40001-025-02407-8
Abstract: Lung adenocarcinoma (LUAD) is one of the most common and lethal tumors. The identification of diagnostic and prognostic biomarkers is essential to improve patient prognosis and treatment outcomes. The expression of minichromosome maintenance complex component… read more here.
Keywords: expression; mcm8 expression; mcm8; lung adenocarcinoma ... See more keywords