Short-lived AIM2 Inflammasome Activation Relates to Chronic MCMV Infection in BALB/c Mice
Sign Up to like & getrecommendations! Published in 2019 at "Current Medical Science"
DOI: 10.1007/s11596-019-2121-4
Abstract: Absent in melanoma 2 (AIM2) inflammasome is a crucial link bridging the innate host defense and the subsequent adaptive immunity when activated by exogenous double stranded DNA (dsDNA). Through establishing models of disseminated murine cytomegalovirus… read more here.
Keywords: day; mcmv; aim2 inflammasome; balb mice ... See more keywords
MXB inhibits murine cytomegalovirus.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.07.017
Abstract: The MX dynamin GTPases inhibit diverse viruses at early post-entry phases. While MXA acts antiviral against influenza viruses, the anti HIV-1 activity of MXB was discovered recently. Here, we have studied the antiviral effect of… read more here.
Keywords: inhibits murine; murine cytomegalovirus; mxb; mcmv ... See more keywords
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00814-5
Abstract: Global pandemics caused by influenza or coronaviruses cause severe disruptions to public health and lead to high morbidity and mortality. There remains a medical need for vaccines against these pathogens. CMV (cytomegalovirus) is a β-herpesvirus… read more here.
Keywords: mcmv; immune; protection; vaccine vectors ... See more keywords
Murine cytomegalovirus infection of mouse macrophages stimulates early expression of suppressor of cytokine signaling (SOCS)1 and SOCS3
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171812
Abstract: Human cytomegalovirus (HCMV) is a species-specific β-herpesvirus that infects for life up to 80% of the world’s population and causes severe morbidity in at-risk immunocompromised populations. Suppressors of cytokine signaling (SOCS)1 and SOCS3 are host… read more here.
Keywords: socs3; mcmv; infection; expression ... See more keywords
UL36 Rescues Apoptosis Inhibition and In vivo Replication of a Chimeric MCMV Lacking the M36 Gene
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00312
Abstract: Apoptosis is an important defense mechanism mounted by the immune system to control virus replication. Hence, cytomegaloviruses (CMV) evolved and acquired numerous anti-apoptotic genes. The product of the human CMV (HCMV) UL36 gene, pUL36 (also… read more here.
Keywords: vivo; apoptosis; mcmv; gene ... See more keywords
Production- and Purification-Relevant Properties of Human and Murine Cytomegalovirus
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13122481
Abstract: There is a large unmet need for a prophylactic vaccine against human cytomegalovirus (HCMV) to combat the ubiquitous infection that is ongoing with this pathogen. A vaccination against HCMV could protect immunocompromised patients and prevent… read more here.
Keywords: mcmv; murine; cytomegalovirus; hcmv ... See more keywords
The Viral G-Protein-Coupled Receptor Homologs M33 and US28 Promote Cardiac Dysfunction during Murine Cytomegalovirus Infection
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15030711
Abstract: Human cytomegalovirus (HCMV) is a ubiquitous pathogen that infects the majority of the world population and causes lifelong latent infection. HCMV has been shown to exacerbate cardiovascular diseases, including myocarditis, vascular sclerosis, and transplant vasculopathy.… read more here.
Keywords: mcmv; infection; dysfunction; m33 ... See more keywords