MCOLN/TRPML channels in the regulation of MTORC1 and autophagy
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DOI: 10.1080/15548627.2023.2300922
Abstract: ABSTRACT MCOLN1 and MCOLN3 are two Ca2+ release channels residing in the endolysosomal membrane. They are activated by phosphatidylinositol (PtdIns)-3-phosphate (PtdIns3P) and/or PtdIns(3,5)P2. Their activities are also regulated by lumenal pH, with low pH enhancing… read more here.
Keywords: autophagy mcoln; mtorc1; mtorc1 activity; mcoln trpml ... See more keywords