Articles with "mcp mod" as a keyword



Closed MCP‐Mod for Pairwise Comparisons of Several Doses With a Control

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Published in 2025 at "Statistics in Medicine"

DOI: 10.1002/sim.70124

Abstract: The MCP‐Mod approach by Bretz et al. is commonly applied for dose–response testing and estimation in clinical trials. The MCP part of MCP‐Mod was originally developed to detect a dose–response signal using a multiple contrast… read more here.

Keywords: mcp mod; dose response; pairwise comparisons; mcp ... See more keywords

Understanding MCP-MOD dose finding as a method based on linear regression.

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Published in 2017 at "Statistics in medicine"

DOI: 10.1002/sim.7424

Abstract: MCP-MOD is a testing and model selection approach for clinical dose finding studies. During testing, contrasts of dose group means are derived from candidate dose response models. A multiple-comparison procedure is applied that controls the… read more here.

Keywords: dose finding; mcp mod; model; linear regression ... See more keywords