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Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70124
Abstract: The MCP‐Mod approach by Bretz et al. is commonly applied for dose–response testing and estimation in clinical trials. The MCP part of MCP‐Mod was originally developed to detect a dose–response signal using a multiple contrast…
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Keywords:
mcp mod;
dose response;
pairwise comparisons;
mcp ... See more keywords
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Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7424
Abstract: MCP-MOD is a testing and model selection approach for clinical dose finding studies. During testing, contrasts of dose group means are derived from candidate dose response models. A multiple-comparison procedure is applied that controls the…
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Keywords:
dose finding;
mcp mod;
model;
linear regression ... See more keywords