Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.05.015
Abstract: Fatty acid esters of 3-chloro-1, 2-propanediol (3-MCPD) are a group of processing-induced food contaminants with nephrotoxicity. This study investigated whether and how necroptosis played a role in the nephrotoxic effect of 3-MCPD-dipalmitate (2.5 g/kg BW) in… read more here.
Keywords: dipalmitate; necroptosis; mir 223; dipalmitate induced ... See more keywords
Potential biomarkers for early detection of 3-MCPD dipalmitate exposure in Sprague Dawley rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c03474
Abstract: 3-Chloro-1,2-propandiol (3-MCPD) dipalmitate is one of the major 3-MCPD esters formed during food processing. In this single-dose study, the metabonomic profile changes in the 48 hours after orally administrated 3-MCPD dipalmitate at 1600 mg/kg BW… read more here.
Keywords: dawley rats; potential biomarkers; mcpd; mcpd dipalmitate ... See more keywords