MCPIP1 inhibits coxsackievirus B3 replication by targeting viral RNA and negatively regulates virus-induced inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-017-0523-0
Abstract: Monocyte chemotactic protein-induced protein 1(MCPIP1) is identified as an important inflammatory regulator during immune response. MCPIP1 possesses antiviral activities against several viruses, such as Japanese encephalitis. However, its role on Coxsackievirus B3 (CVB3) infection, a… read more here.
Keywords: mcpip1 inhibits; cvb3 infection; rna; mcpip1 ... See more keywords
MCPIP1 regulates focal adhesion kinase and rho GTPase-dependent migration in clear cell renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174804
Abstract: Metastasis is responsible for as many as 90% of cancer-associated deaths in patients. The metastatic process is a result of tumor cell migration and invasion associated with morphological changes and increased expression of several genes… read more here.
Keywords: renal cell; cell renal; migration; mcpip1 ... See more keywords
MCPIP1 reduces HBV-RNA by targeting its epsilon structure
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-77166-z
Abstract: Hepatitis B virus (HBV) is the major causative factor of chronic viral hepatitis, liver cirrhosis, and hepatocellular carcinoma. We previously demonstrated that a proinflammatory cytokine IL-1β reduced the level of HBV RNA. However, the mechanism… read more here.
Keywords: hbv rna; mcpip1; epsilon structure;
PRRSV Nsp11 Antagonizes Broad Antiviral Effects of MCPIP1 via Inducing IL-17 Expression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of virology"
DOI: 10.1128/jvi.01119-21
Abstract: Monocyte chemotactic protein-induced protein 1 (MCPIP1) is an inflammatory regulator in immune response and has broad antiviral effects by targeting viral RNA. Porcine reproductive and respiratory syndrome virus (PRRSV), a major viral pathogen in pigs,… read more here.
Keywords: expression; prrsv nsp11; prrsv; infection ... See more keywords
Role of MCPIP1 protein in lipid metabolism, liver homeostasis and non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Postepy biochemii"
DOI: 10.18388/pb.2021_446
Abstract: Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive accumulation of lipids in hepatocytes. Among NAFLD patients, in 25% of them this disease progress to nonalcoholic steatohepatitis, which is characterized additionally by the development of… read more here.
Keywords: mcpip1; alcoholic fatty; liver; non alcoholic ... See more keywords