Articles with "mcr" as a keyword



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Investigation of potential risk factors for the occurrence of Escherichia coli isolates from German fattening pig farms harbouring the mcr-1 colistin-resistance gene.

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Published in 2018 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2017.08.007

Abstract: Within the scope of a cross-sectional investigation on fattening pig farms conducted in 2011 and 2012, 48 fattening farms in different agricultural regions of Germany were sampled. Primary cultures of boot swabs and collective faecal… read more here.

Keywords: mcr colistin; colistin resistance; pig farms; fattening pig ... See more keywords
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Impact of the colistin resistance gene mcr-1 on bacterial fitness.

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Published in 2018 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2017.11.011

Abstract: A Klebsiella pneumoniae isolate harbouring a 217 kb IncHI2-type plasmid (pKP2442) encoding the colistin resistance gene mcr-1 was isolated from a leukaemia patient. pKP2442 was mobilised by intragenus and intergenus transconjugation from the clinical isolate… read more here.

Keywords: resistance gene; colistin resistance; resistance; fitness ... See more keywords
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Prevalence of mobile colistin resistance (mcr) genes in extended-spectrum β-lactamase-producing Escherichia coli isolated from retail raw foods in Nha Trang, Vietnam.

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Published in 2021 at "International journal of food microbiology"

DOI: 10.1016/j.ijfoodmicro.2021.109164

Abstract: The aim of the study was to assess the presence of genes in ESBL-producing E. coli (ESBL-Ec) isolated from retail raw food in Nha Trang, Vietnam. A total of 452 food samples comprising chicken (n = 116),… read more here.

Keywords: esbl isolates; mcr mcr; mcr genes; mcr ... See more keywords
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A SYBR® Green-based real-time PCR method for improved detection of mcr-1-mediated colistin resistance in human stool samples.

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Published in 2017 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2017.01.007

Abstract: OBJECTIVES The aim of this study was to design a rapid and sensitive real-time PCR (rt-PCR) method for colistin resistance mcr-1 gene detection in human faecal samples. METHODS Stools (n=88) from 36 volunteers were analysed.… read more here.

Keywords: detection; real time; colistin; pcr ... See more keywords
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Co-occurrence of mcr-1 mediated colistin resistance and β-lactamases encoding genes in Multidrug-resistant Escherichia coli from broiler chickens with colibacillosis in Tunisia.

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Published in 2020 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2020.03.017

Abstract: OBJECTIVES Colibacillosis caused by avian pathogenic E. coli (APEC) is considered as a major hindrance in poultry farming worldwide. This study aimed to characterize the genetic content and the relatedness between multidrug-resistant E. coli isolates… read more here.

Keywords: colibacillosis; coli isolates; coli; resistance ... See more keywords
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Draft genome sequence of mcr-1-mediated colistin-resistant Escherichia coli ST359 from chicken carcasses in Northeastern Brazil.

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Published in 2020 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2020.08.016

Abstract: OBJECTIVES Considering that polymyxin is a drug of last resort in the treatment of humans infected by multidrug-resistant bacteria, the occurrence of plasmid-mediated colistin resistance mcr gene among Gram-negative bacteria in foods must be investigated.… read more here.

Keywords: coli; colistin resistant; mcr; mediated colistin ... See more keywords
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Mobile colistin resistance gene mcr-1 is detected on an IncI1 plasmid in E. coli from meat.

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Published in 2020 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2020.08.018

Abstract: OBJECTIVES Mobile colistin resistance genes (mcr) encoded on conjugative plasmids, although described only relatively recently, have been reported globally in both humans and livestock. The genes are often associated with ISApl1 which can transpose the… read more here.

Keywords: inci1 plasmid; colistin resistance; mobile colistin; mcr ... See more keywords
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Genomic characterization of clinical Enterobacter roggenkampii co-harboring blaIMP-1- and blaGES-5-encoding IncP6 and mcr-9-encoding IncHI2 plasmids isolated in Japan.

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Published in 2020 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2020.11.028

Abstract: OBJECTIVES The spread of carbapenemase-producing Enterobacterales (CPE) with colistin resistance is a critical public health issue. We genetically characterized the clinical isolate Enterobacter roggenkampii OIPH-N260, which harbored carbapenemase genes blaIMP-1 and blaGES-5 with multiple resistance… read more here.

Keywords: blages encoding; resistance; mcr; blaimp blages ... See more keywords
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Decreased colistin resistance and mcr-1 prevalence in pig-derived Escherichia coli in Japan after banning colistin as a feed additive.

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Published in 2021 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2021.01.016

Abstract: BACKGROUND Antimicrobial resistance to colistin, a widely used feed additive for farm animals across the world, has raised public health concern in recent years. Since July 2018, its use as feed additive has been banned… read more here.

Keywords: colistin; colistin resistance; coli; resistance ... See more keywords
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Global Prevalence and Molecular Epidemiology of mcr-Mediated Colistin Resistance in Escherichia coli Clinical Isolates: A Systematic Review.

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Published in 2021 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2021.10.022

Abstract: BACKGROUND AND AIM The continuing rise in infections caused by multi-drug resistant (MDR) bacteria is one of the most serious public health issues in today's societies. Colistin is a last-resort antimicrobial medication used to treat… read more here.

Keywords: prevalence; colistin resistance; epidemiology; resistance ... See more keywords
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Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France.

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Published in 2022 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2022.01.014

Abstract: INTRODUCTION Colistin is considered last resort antibiotic against carbapenem-resistant isolates. Nowadays, this antibiotic is facing the emergence of mobilised colistin resistance (mcr) genes which confer colistin resistance. OBJECTIVE Genomic characterisation of an atypical multidrug-resistant Escherichia… read more here.

Keywords: mcr; escherichia coli; mcr genes; mcr mcr ... See more keywords