Detection of E. coli IncX1 Plasmid-Mediated mcr-5.1 Gene in an Indian Hospital Sewage Water Using Shotgun Metagenomic Sequencing: A First Report.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0338
Abstract: Colistin is used against a multitude of multidrug-resistant and extremely drug-resistant Gram-negative bacterial infections. The emergence of colistin resistance is highly concerning as it may lead to the failure of this last-resort antibiotic. Since the… read more here.
Keywords: sewage water; gene; mcr gene; hospital sewage ... See more keywords
Complete genome sequencing revealed novel genetic contexts of the mcr-1 gene in Escherichia coli strains
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw541
Abstract: Sir, Polymyxin-based treatment is often considered as the last-line therapy for MDR Gram-negative bacterial infections. Resistance to polymyxins, in particular colistin, was previously linked to adaptive or mutational mechanisms involving chromosomally encoded genes before the… read more here.
Keywords: isapl1; dpap; mcr gene; resistance ... See more keywords
Functional Characterization of a Miniature Inverted Transposable Element at the Origin of mcr-5 Gene Acquisition in Escherichia coli
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00559-19
Abstract: Plasmid-mediated colistin resistance of the mobile colistin resistance (MCR) type is a growing concern in Enterobacteriaceae since it has been described worldwide in humans and animals. Here, we identified a series of MCR-producing Escherichia coli… read more here.
Keywords: mcr; mcr gene; gene; escherichia coli ... See more keywords
Detection of mcr-1 Gene among Escherichia coli Isolates from Farmed Fish and Characterization of mcr-1-Bearing IncP Plasmids
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02378-17
Abstract: ABSTRACT The presence of the mcr-1 gene in Escherichia coli isolated from retail freshwater fish was investigated. Seven (3.65%) clonally unrelated original E. coli isolates from grass carp were positive for mcr-1. The mcr-1 genes… read more here.
Keywords: escherichia coli; coli isolates; mcr gene; incp plasmids ... See more keywords
Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02623-16
Abstract: ABSTRACT Since colistin resistance based on the plasmid-encoded mcr-1 gene was first described, this resistance gene in Enterobacteriaceae has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity.… read more here.
Keywords: escherichia coli; gene; detection mcr; mcr gene ... See more keywords
Global Distribution of mcr Gene Variants in 214K Metagenomic Samples
Sign Up to like & getrecommendations! Published in 2022 at "mSystems"
DOI: 10.1128/msystems.00105-22
Abstract: The ever-growing collection of metagenomic samples available in public data repositories has the potential to reveal new details on the emergence and dissemination of mobilized colistin resistance genes. Our analysis of metagenomes deposited online in… read more here.
Keywords: mcr; metagenomic samples; gene; distribution mcr ... See more keywords
Longitudinal study of the mcr-1 gene prevalence in Spanish food-producing pigs from 1998 to 2021 and its relationship with the use of polymyxins
Sign Up to like & getrecommendations! Published in 2022 at "Porcine Health Management"
DOI: 10.1186/s40813-022-00255-0
Abstract: Background Resistance to colistin was an uncommon phenomenon traditionally linked to chromosome point mutations, but since the first description of a plasmid-mediated colistin-resistance in late 2015, transmissible resistance to colistin has become a Public Health… read more here.
Keywords: colistin resistance; resistance; mcr gene; colistin ... See more keywords
First clinical isolate of Escherichia coli harboring mcr-1 gene in Mexico
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0214648
Abstract: Our aim in this report was to describe the characteristics of the first clinical isolate of Escherichia coli (EC-PAG-733) harboring the mcr-1 gene found in Mexico. This isolate was obtained from a fecal sample from… read more here.
Keywords: escherichia coli; isolate; mcr gene;
Detection of the mcr-1 gene in Enteropathogenic Escherichia coli (EPEC) and Shigatoxigenic E. coli (STEC) strains isolated from broilers
Sign Up to like & getrecommendations! Published in 2020 at "Pesquisa Veterinaria Brasileira"
DOI: 10.1590/1678-5150-pvb-5983
Abstract: ABSTRACT: Enteropathogenic Escherichia coli (EPEC) and Shigatoxigenic E. coli (STEC) strains are among the major pathotypes found in poultry and their products, which are capable of causing human enteric infections. Colistin has been claimed the… read more here.
Keywords: stec strains; enteropathogenic escherichia; epec; coli ... See more keywords
Prevalence and molecular characteristics of mcr-1 colistin resistance in Escherichia coli: isolates of clinical infection from a Chinese University Hospital
Sign Up to like & getrecommendations! Published in 2018 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s166726
Abstract: Background Colistin has been considered as one of the most effective treatments in clinical infections, especially multidrug-resistant (MDR) bacteria-infected patients. The mcr-1 gene leads to polymyxin resistance in China. The present study investigated the prevalence… read more here.
Keywords: escherichia coli; hospital; mcr gene; resistance ... See more keywords
Prevalence and molecular characteristics of mcr-1 gene in Salmonella typhimurium in a tertiary hospital of Zhejiang Province
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s190269
Abstract: Objectives mcr-1 gene has been widely reported in the world. This study aimed to analyze the prevalence and molecular characteristics of mcr-1 gene in Salmonella typhimurium from Quzhou People's Hospital. Materials and methods A total… read more here.
Keywords: mcr positive; prevalence molecular; typhimurium; mcr gene ... See more keywords