Prevalence of mobile colistin resistance (mcr) genes in extended-spectrum β-lactamase-producing Escherichia coli isolated from retail raw foods in Nha Trang, Vietnam.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of food microbiology"
DOI: 10.1016/j.ijfoodmicro.2021.109164
Abstract: The aim of the study was to assess the presence of genes in ESBL-producing E. coli (ESBL-Ec) isolated from retail raw food in Nha Trang, Vietnam. A total of 452 food samples comprising chicken (n = 116),… read more here.
Keywords: esbl isolates; mcr mcr; mcr genes; mcr ... See more keywords
Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2021.07.021
Abstract: Colistin is one of our last line of therapy against multi-drug resistant Gram-nevative pathogens especially carbapenemases producers, which makes from resistance to this compound a major global public health crisis. Until recently, colistin resistance in… read more here.
Keywords: water; colistin resistance; epidemiology; resistance ... See more keywords
Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.01.014
Abstract: INTRODUCTION Colistin is considered last resort antibiotic against carbapenem-resistant isolates. Nowadays, this antibiotic is facing the emergence of mobilised colistin resistance (mcr) genes which confer colistin resistance. OBJECTIVE Genomic characterisation of an atypical multidrug-resistant Escherichia… read more here.
Keywords: mcr; escherichia coli; mcr genes; mcr mcr ... See more keywords
Plasmid-Mediated Colistin Resistance Genes mcr-1 and mcr-4 in Multidrug-Resistant Escherichia coli Strains Isolated from a Healthy Pig in Portugal.
Sign Up to like & getrecommendations! Published in 2023 at "Microbial drug resistance"
DOI: 10.1089/mdr.2022.0228
Abstract: Antimicrobial resistance encoded by mobile colistin resistance (mcr) genes is a global and emergent threat. In this study, we report the occurrence of two different populations of colistin-resistant Escherichia coli harboring mcr-1 and mcr-4 variants… read more here.
Keywords: pig; mcr; resistance; mcr genes ... See more keywords
Loss of mcr Genes Mediated by Plasmid Elimination and ISApl1
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01002-19
Abstract: We characterized the stability of a plasmid pCP53-mcr1_3 encoding mcr-1 and mcr-3.19 with and without colistin exposure during cultural passages via S1-pulsed-field gel electrophoresis (PFGE) and nanopore MinION sequencing. Both mcr-1 and mcr-3.19 were missing… read more here.
Keywords: mcr; plasmid elimination; elimination; mcr mcr ... See more keywords
Emergence of Colistin Resistance Gene mcr-10 in Enterobacterales Isolates Recovered from Fecal Samples of Chickens, Slaughterhouse Workers, and a Nearby Resident
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00418-22
Abstract: We discovered mcr-10-harboring isolates in the “one health” approach and reported for the first time multidrug-resistant clinically threatening ST11 K. pneumoniae isolates coharboring mcr-10 and mcr-8 genes that are resistant to polymyxins and show reduced… read more here.
Keywords: mcr; harboring isolates; mcr harboring; mcr genes ... See more keywords
Escherichia coli B-Strains Are Intrinsically Resistant to Colistin and Not Suitable for Characterization and Identification of mcr Genes
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00894-23
Abstract: Given the rise in multidrug, extensive drug, and pandrug resistance in bacteria and the increasing use of colistin to treat human infections, occurrence of mcr genes threatens human health, and characterization of these resistance genes… read more here.
Keywords: colistin; resistance; mcr genes; coli strains ... See more keywords
Distribution and Transmission of Colistin Resistance Genes mcr-1 and mcr-3 among Nontyphoidal Salmonella Isolates in China from 2011 to 2020
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03833-22
Abstract: Nontyphoidal Salmonella is one of four major causative agents of diarrheal diseases globally, with most cases of salmonellosis being mild. Antimicrobial treatments are required for cases of life-threatening infections, and colistin is one of the… read more here.
Keywords: nontyphoidal salmonella; salmonella isolates; mcr; transmission ... See more keywords
Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface
Sign Up to like & getrecommendations! Published in 2020 at "Gut Pathogens"
DOI: 10.1186/s13099-020-00392-3
Abstract: Background The global emergence of plasmid-mediated colistin resistance (Col-R) conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment option for multidrug-resistant bacterial infections in humans. This study aimed to assess the… read more here.
Keywords: genes gram; emergence plasmid; plasmid mediated; mcr genes ... See more keywords
Low Level of Colistin Resistance and mcr Genes Presence in Salmonella spp.: Evaluation of Isolates Collected between 2000 and 2020 from Animals and Environment
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11020272
Abstract: Salmonellosis is one of the most important zoonoses in Europe and the world. Human infection may evolve in severe clinical diseases, with the need for hospitalization and antimicrobial treatment. Colistin is now considered an important… read more here.
Keywords: mcr; resistance; colistin; mcr genes ... See more keywords
Global Variation in Escherichia coli mcr-1 Genes and Plasmids from Animal and Human Genomes Following Colistin Usage Restrictions in Livestock
Sign Up to like & getrecommendations! Published in 2024 at "Antibiotics"
DOI: 10.3390/antibiotics13080759
Abstract: Antimicrobial resistance (AMR) is a significant global health threat, with multidrug-resistant (MDR) bacterial clones becoming a major concern. Polymyxins, especially colistin, have reemerged as last-resort treatments for MDR Gram-negative infections. However, colistin use in livestock… read more here.
Keywords: escherichia coli; following colistin; colistin; livestock ... See more keywords