Prevalence of mobile colistin resistance (mcr) genes in extended-spectrum β-lactamase-producing Escherichia coli isolated from retail raw foods in Nha Trang, Vietnam.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of food microbiology"
DOI: 10.1016/j.ijfoodmicro.2021.109164
Abstract: The aim of the study was to assess the presence of genes in ESBL-producing E. coli (ESBL-Ec) isolated from retail raw food in Nha Trang, Vietnam. A total of 452 food samples comprising chicken (n = 116),… read more here.
Keywords: esbl isolates; mcr mcr; mcr genes; mcr ... See more keywords
Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.01.014
Abstract: INTRODUCTION Colistin is considered last resort antibiotic against carbapenem-resistant isolates. Nowadays, this antibiotic is facing the emergence of mobilised colistin resistance (mcr) genes which confer colistin resistance. OBJECTIVE Genomic characterisation of an atypical multidrug-resistant Escherichia… read more here.
Keywords: mcr; escherichia coli; mcr genes; mcr mcr ... See more keywords
Pyrazolones Potentiate Colistin Activity against MCR-1-Producing Resistant Bacteria: Computational and Microbiological Study
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DOI: 10.1021/acsomega.2c07165
Abstract: The polymyxin colistin is a last line antibiotic for extensively resistant Gram-negative bacteria. Colistin binding to lipid A disrupts the Gram-negative outer membrane, but mobile colistin resistance (mcr) gene family members confer resistance by catalyzing… read more here.
Keywords: mcr; mcr mcr; colistin; activity ... See more keywords
Plasmid-mediated colistin resistance and ESBL production in Escherichia coli from clinically healthy and sick pigs
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DOI: 10.1038/s41598-022-06415-0
Abstract: This study aimed to determine the percentage of colistin resistant and ESBL-producing Escherichia coli from clinically sick and healthy pigs and understand the molecular mechanisms underlying colistin resistance and ESBL production. A total of 454… read more here.
Keywords: mcr; colistin resistance; sick pigs; healthy sick ... See more keywords
Molecular Insights into Functional Differences between mcr-3- and mcr-1-Mediated Colistin Resistance
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00366-18
Abstract: The global emergence of plasmid-mediated colistin resistance genes mcr-1 and mcr-3 has threatened the role of the “last-resort” drug colistin in the defense against infections caused by multidrug-resistant Gram-negative bacteria. However, functional differences between these… read more here.
Keywords: mcr mcr; colistin resistance; functional differences; mcr ... See more keywords
Loss of mcr Genes Mediated by Plasmid Elimination and ISApl1
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01002-19
Abstract: We characterized the stability of a plasmid pCP53-mcr1_3 encoding mcr-1 and mcr-3.19 with and without colistin exposure during cultural passages via S1-pulsed-field gel electrophoresis (PFGE) and nanopore MinION sequencing. Both mcr-1 and mcr-3.19 were missing… read more here.
Keywords: mcr; plasmid elimination; elimination; mcr mcr ... See more keywords
Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes
Sign Up to like & getrecommendations! Published in 2018 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2018.23.6.17-00672
Abstract: Background and aim Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 to mcr-5,… read more here.
Keywords: detection; mcr mcr; colistin resistance; multiplex pcr ... See more keywords
Occurrence of mcr-1 and mcr-2 colistin resistance genes in porcine Escherichia coli isolates (2010–2020) and genomic characterization of mcr-2-positive E. coli
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1076315
Abstract: Introduction The global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria. To date, ten mcr-genes (mcr-1 to mcr-10) were reported.… read more here.
Keywords: occurrence mcr; mcr; coli isolates; mcr mcr ... See more keywords
Low Level of Colistin Resistance and mcr Genes Presence in Salmonella spp.: Evaluation of Isolates Collected between 2000 and 2020 from Animals and Environment
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11020272
Abstract: Salmonellosis is one of the most important zoonoses in Europe and the world. Human infection may evolve in severe clinical diseases, with the need for hospitalization and antimicrobial treatment. Colistin is now considered an important… read more here.
Keywords: mcr; resistance; colistin; mcr genes ... See more keywords
Mobile Colistin Resistance (mcr) Genes in Cats and Dogs and Their Zoonotic Transmission Risks
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DOI: 10.3390/pathogens11060698
Abstract: Background: Pets, especially cats and dogs, represent a great potential for zoonotic transmission, leading to major health problems. The purpose of this systematic review was to present the latest developments concerning colistin resistance through mcr… read more here.
Keywords: zoonotic transmission; mcr; mcr mcr; transmission ... See more keywords