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Published in 2021 at "International journal of food microbiology"
DOI: 10.1016/j.ijfoodmicro.2021.109164
Abstract: The aim of the study was to assess the presence of genes in ESBL-producing E. coli (ESBL-Ec) isolated from retail raw food in Nha Trang, Vietnam. A total of 452 food samples comprising chicken (n = 116),…
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Keywords:
esbl isolates;
mcr mcr;
mcr genes;
mcr ... See more keywords
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Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.01.014
Abstract: INTRODUCTION Colistin is considered last resort antibiotic against carbapenem-resistant isolates. Nowadays, this antibiotic is facing the emergence of mobilised colistin resistance (mcr) genes which confer colistin resistance. OBJECTIVE Genomic characterisation of an atypical multidrug-resistant Escherichia…
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Keywords:
mcr;
escherichia coli;
mcr genes;
mcr mcr ... See more keywords
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Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07165
Abstract: The polymyxin colistin is a last line antibiotic for extensively resistant Gram-negative bacteria. Colistin binding to lipid A disrupts the Gram-negative outer membrane, but mobile colistin resistance (mcr) gene family members confer resistance by catalyzing…
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Keywords:
mcr;
mcr mcr;
colistin;
activity ... See more keywords
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Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-06415-0
Abstract: This study aimed to determine the percentage of colistin resistant and ESBL-producing Escherichia coli from clinically sick and healthy pigs and understand the molecular mechanisms underlying colistin resistance and ESBL production. A total of 454…
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Keywords:
mcr;
colistin resistance;
sick pigs;
healthy sick ... See more keywords
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Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00366-18
Abstract: The global emergence of plasmid-mediated colistin resistance genes mcr-1 and mcr-3 has threatened the role of the “last-resort” drug colistin in the defense against infections caused by multidrug-resistant Gram-negative bacteria. However, functional differences between these…
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Keywords:
mcr mcr;
colistin resistance;
functional differences;
mcr ... See more keywords
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Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01002-19
Abstract: We characterized the stability of a plasmid pCP53-mcr1_3 encoding mcr-1 and mcr-3.19 with and without colistin exposure during cultural passages via S1-pulsed-field gel electrophoresis (PFGE) and nanopore MinION sequencing. Both mcr-1 and mcr-3.19 were missing…
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Keywords:
mcr;
plasmid elimination;
elimination;
mcr mcr ... See more keywords
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Published in 2018 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2018.23.6.17-00672
Abstract: Background and aim Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 to mcr-5,…
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Keywords:
detection;
mcr mcr;
colistin resistance;
multiplex pcr ... See more keywords
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Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1076315
Abstract: Introduction The global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria. To date, ten mcr-genes (mcr-1 to mcr-10) were reported.…
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Keywords:
occurrence mcr;
mcr;
coli isolates;
mcr mcr ... See more keywords
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Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11020272
Abstract: Salmonellosis is one of the most important zoonoses in Europe and the world. Human infection may evolve in severe clinical diseases, with the need for hospitalization and antimicrobial treatment. Colistin is now considered an important…
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Keywords:
mcr;
resistance;
colistin;
mcr genes ... See more keywords
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Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11060698
Abstract: Background: Pets, especially cats and dogs, represent a great potential for zoonotic transmission, leading to major health problems. The purpose of this systematic review was to present the latest developments concerning colistin resistance through mcr…
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Keywords:
zoonotic transmission;
mcr;
mcr mcr;
transmission ... See more keywords