The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32045
Abstract: Tumour cell anaerobic metabolism has been reported to be a prognostic factor in colorectal cancer. The present study investigated the association between monocarboxylate transporter (MCT) 1, MCT 2, lactate dehydrogenase (LDH) 1 and LDH 5,… read more here.
Keywords: mct; tumour cell; tumour microenvironment; colorectal cancer ... See more keywords
Generation of monoclonal antibodies against mitocryptide‐2: toward a new strategy to investigate the biological roles of cryptides
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.3000
Abstract: We recently identified a novel family of neutrophil‐activating peptides including mitocryptide‐1 and mitocryptide‐2 (MCT‐2) that are endogenously produced from various mitochondrial proteins. Among them, MCT‐2 is an N‐formylated pentadecapeptide derived from mitochondrial cytochrome b and… read more here.
Keywords: mct; mitocryptide toward; antibodies mitocryptide; toward new ... See more keywords
A comparison of the satiating properties of medium-chain triglycerides and conjugated linoleic acid in participants with healthy weight and overweight or obesity
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nutrition"
DOI: 10.1007/s00394-020-02235-y
Abstract: Purpose Inconsistent evidence exists for greater satiety after medium-chain triglycerides (MCT) or conjugated linoleic acid (CLA) compared to long-chain triglycerides (LCT). Furthermore, the mechanisms are poorly understood and effects in people with a healthy weight… read more here.
Keywords: mct; overweight obesity; chain triglycerides; healthy weight ... See more keywords
Safety of Discontinuing Asthma Treatment Before Performing a Methacholine Challenge Test
Sign Up to like & getrecommendations! Published in 2017 at "Archivos De Bronconeumologia"
DOI: 10.1016/j.arbr.2017.03.020
Abstract: The methacholine challenge test (MCT) is a diagnostic test required in many cases of suspected asthma.1,2 GEMA and GINA guidelines state that is more useful for ruling out asthma than for confirming it, but neither… read more here.
Keywords: mct; test; treatment; challenge test ... See more keywords
Propofol improves colonic but impairs hepatic mitochondrial function in tissue homogenates from healthy rats
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.04.031
Abstract: ABSTRACT Evidence suggests that propofol infusion syndrome (PRIS) is caused by an altered mitochondrial function. The aim of this study was to examine the effects of propofol and the vehicle MCT on mitochondrial function in… read more here.
Keywords: mct; propofol mct; mitochondrial function; complex ... See more keywords
Liquiritigenin and liquiritin alleviated MCT‐induced HSOS by activating Nrf2 antioxidative defense system
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.06.014
Abstract: ABSTRACT Hepatic sinusoidal obstruction syndrome (HSOS) is a serious and life‐threatening liver disease. Liquiritigenin (LG) and liquiritin (LQ) are natural flavonoids distributed in Glycyrrhizae Radix et Rhizoma (Gan‐cao). This study aims to investigate the protective… read more here.
Keywords: mct; mct induced; liquiritigenin liquiritin; nrf2 antioxidative ... See more keywords
Thromboxane A2 receptor signaling in endothelial cells attenuates monocrotaline-induced liver injury.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114733
Abstract: Sinusoidal obstruction syndrome (SOS) is a major complication of chemotherapy and hematopoietic stem cell transplantation. The early stage of SOS is characterized by liver sinusoidal endothelial cell (LSEC) injury accompanied by platelet aggregation. Thromboxane A2… read more here.
Keywords: mct; induced liver; thromboxane; liver injury ... See more keywords
The effect of triglyceride chain length combined with exercise on appetite, satiety and energy balance
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665118001623
Abstract: Medium chain triglycerides (MCT) have been shown to increase energy expenditure as well as increase satiety and suppress food intake. The effects of exercise on appetite regulation are equivocal, but it is well documented that… read more here.
Keywords: mct; energy expenditure; energy; satiety ... See more keywords
Appetite and physiological responses to medium-chain triglycerides (MCT) and conjugated linoleic acid (CLA) in lean vs overweight/obese participants
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665120000580
Abstract: Abstract Medium-chain triglycerides (MCT) are lipids which have been shown to yield appetite-suppressing properties compared to long-chain triglycerides (LCT), which are more commonly found in the diet. Conjugated linoleic acid (CLA) has also been shown… read more here.
Keywords: overweight obese; chain triglycerides; medium chain; cla ... See more keywords
Inflammation Intensifies Monocrotaline-Induced Liver Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07939
Abstract: Pyrrolizidine alkaloids (PAs) are the most common toxins of plant origin, and it is evident that PAs pollute soil, water, nearby plants, and derived foods. Cases of human poisoning due to ingestion of PA-contaminated foods… read more here.
Keywords: inflammation; liver injury; mct; mpo ... See more keywords
Growth-Inhibiting, Bactericidal, Antibiofilm, and Urease Inhibitory Activities of Hibiscus rosa sinensis L. Flower Constituents toward Antibiotic Sensitive- and Resistant-Strains of Helicobacter pylori
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c01640
Abstract: The aim of the present study was to assess antimicrobial effects of naringenin (NRG), luteolin (LUT), myricetin (MCT), and protocatechuic acid (PCA) identified in a Hibiscus rosa sinensis flower against two reference strains and five… read more here.
Keywords: mct; rosa sinensis; sinensis flower; hibiscus rosa ... See more keywords