Celastrol reverses palmitic acid (PA)‐caused TLR4‐MD2 activation‐dependent insulin resistance via disrupting MD2‐related cellular binding to PA
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DOI: 10.1002/jcp.26547
Abstract: Elevated plasma statured fatty acids (FFAs) cause TLR4/MD2 activation‐dependent inflammation and insulin tolerance, which account for the occurrence and development of obesity. It has been confirmed that statured palmitic acid (PA) (the most abundant FFA)… read more here.
Keywords: md2; insulin; celastrol; md2 activation ... See more keywords