Lung‐specific exosomes for doxorubicin delivery in lung adenocarcinoma therapy
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology Journal"
DOI: 10.1002/biot.202300296
Abstract: Doxorubicin (DOX) could be utilized to treat lung adenocarcinoma (LUAD), while dose‐limiting cardiotoxicity limits its clinical utilization. MDA‐MB‐231 cell‐derived exosomes show lung‐specific organotropism features. In this study, we aimed to explore the potential of MDA‐MB‐231… read more here.
Keywords: lung; lung specific; lung adenocarcinoma; delivery ... See more keywords
Invasion and migration of MDA‐MB‐231 cells are inhibited by block of AhR and NFAT: role of AhR/NFAT1/β4 integrin signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3728
Abstract: Benzo[α]pyrene (BaP) can have significant role in the development of breast cancer via aryl hydrocarbon receptor (AhR) activation. AhR activation has been studied in several functions such as survival, migration and invasion of cancer cells.… read more here.
Keywords: 231 cells; mda 231; invasion; migration mda ... See more keywords
Genetic and small molecule inhibition of arylamine N‐acetyltransferase 1 reduces anchorage‐independent growth in human breast cancer cell line MDA‐MB‐231
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22779
Abstract: Arylamine N‐acetyltransferase 1 (NAT1) expression is reported to affect proliferation, invasiveness, and growth of cancer cells. MDA‐MB‐231 breast cancer cells were engineered such that NAT1 expression was elevated or suppressed, or treated with a small… read more here.
Keywords: cell line; cell; mda 231; cancer ... See more keywords
Directional Migration of MDA-MB-231 Cells Under O2/pH Gradients.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-55231-6_23
Abstract: We hypothesized that cancer cells actively migrate toward intratumor microvessels, guided by tissue gradients of metabolic substrates (such as O2) and/or metabolites (such as CO2/H+). To test this hypothesis, we developed an in vitro model… read more here.
Keywords: directional migration; 231 cells; mda 231; migration mda ... See more keywords
Changes in the Metastatic Properties of MDA-MB-231 Cells after IGFBP6 Gene Knockdown Is Associated with Increased Expression of miRNA Genes Controlling INSR, IGF1R, and CCND1 Genes
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04409-z
Abstract: Metastatic cascade is associated with the process of epithelial-mesenchymal transition accompanied by changes in cell proliferation, migration, adhesion, and invasiveness mediated by the insulin-like growth factor (IGF) signal pathway. IGFBP6 protein binds IGF and prevents… read more here.
Keywords: igfbp6 gene; mda 231; gene knockdown; insr ... See more keywords
BET-directed PROTACs in triple negative breast cancer cell lines MDA-MB-231 and MDA-MB-436
Sign Up to like & getrecommendations! Published in 2024 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-024-07403-w
Abstract: This study aims to find whether the proliferation and migration of triple negative breast cancer (TNBC) cell lines can be reduced by treatment with bromodomain and extra-terminal domain (BET) inhibitor JQ1 and BET protein targeting… read more here.
Keywords: cancer; breast cancer; mda 231; cell ... See more keywords
ERβ modulates genistein’s cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03505-y
Abstract: As one of the typical food-derived phytoestrogens, genistein (GEN) could bind to estrogen receptor (ER) and was reported to be closely related to breast cancer. Our former research showed that GEN interfered with the anti-tumor… read more here.
Keywords: cis; mda 231; gen; breast cancer ... See more keywords
Targeting signaling pathways of VEGFR1 and VEGFR2 as a potential target in the treatment of breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05306-9
Abstract: Tumor angiogenesis allows tumor cells to grow and migrate toward the bloodstream and initiate metastasis. The interactions of vascular endothelial growth factors (VEGF) A and B, as the important regulating factors for blood vessel growth,… read more here.
Keywords: signaling pathways; 231 cells; mda 231; vegfr1 vegfr2 ... See more keywords
Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-020-01447-0
Abstract: Triple negative breast cancer (TNBC) is the most severe type of breast cancer due to the lack of specific targets and rapid metastasis, which result in the poor prognosis. Recently, phosphatidylinositol 3-kinase (PI3K)/Akt pathway has… read more here.
Keywords: 231 cells; wikstroemia indica; wikstromol wikstroemia; mda 231 ... See more keywords
Extracts of Hypsizygus tessellatus (white var.) caps inhibited MCF-7 and MDA-MB-231 cell lines proliferation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Food Measurement and Characterization"
DOI: 10.1007/s11694-018-9952-8
Abstract: Cancer management is associated with serious side-effects due to the harmful nature of radiation and chemotherapy on the body cells. These side-effects have necessitated the need for diversifying the alternative or complementary sources of cancer… read more here.
Keywords: white var; mda; mda 231; ic50 ... See more keywords
High-throughput, Label-free Proteomics Identifies Salient Proteins and Genes in MDA-MB-231 Cells Treated with Natural Neem-based Electrochemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03787-3
Abstract: With the absence of the three most common receptor targets, and with high vascularity and higher-grade tumors, triple-negative breast cancer (TNBC) is the most aggressive of all breast cancer subtypes and is in need of… read more here.
Keywords: throughput label; tnbc; label free; mda 231 ... See more keywords