Novel thiosemicarbazones induce high toxicity in estrogen-receptor-positive breast cancer cells (MCF7) and exacerbate cisplatin effectiveness in triple-negative breast (MDA-MB231) and lung adenocarcinoma (A549) cells
Sign Up to like & getrecommendations! Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00789-1
Abstract: Cis-diamminedichloroplatinum(II) (CDDP), known as cisplatin, has been extensively used against breast cancer, which is the most frequent cancer among women, and lung cancer, the leading cancer that causes death worldwide. Novel compounds such as thiazole… read more here.
Keywords: mda mb231; breast; a549; breast cancer ... See more keywords
Breast cancer induced nociceptor aberrant growth and collateral sensory axonal branching
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DOI: 10.18632/oncotarget.20609
Abstract: The tumour and neuron interaction has a significant impact upon disease progression and the patients quality of life. In breast cancer patients, it is known that there is an interaction between the tumour microenvironment and… read more here.
Keywords: cancer; mda mb231; growth; breast cancer ... See more keywords
12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of oncology"
DOI: 10.3892/ijo.2018.4378
Abstract: Metastasising breast cancer cells communicate with adjacent lymph endothelia, intravasate and disseminate through lymphatic routes, colonise lymph nodes and finally metastasize to distant organs. Thus, understanding and blocking intravasation may attenuate the metastatic cascade at… read more here.
Keywords: mda mb231; sox18; retraction; intravasation ... See more keywords
Long non-coding RNA HOTAIR enhances radioresistance in MDA-MB231 breast cancer cells
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DOI: 10.3892/ol.2017.5587
Abstract: The aim of the present study was to investigate the radiosensitizing effects of homeobox (HOX) transcript antisense RNA (HOTAIR) long non-coding RNA on breast cancer tumor cells and examine the underlying mechanisms. Recombinant plasmid vectors… read more here.
Keywords: mda mb231; hotair; breast cancer;