Serum KL‐6 level is a prognostic marker in patients with anti‐MDA5 antibody‐positive dermatomyositis associated with interstitial lung disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22978
Abstract: This study aimed to investigate the clinical significance of Krebs von den Lungen‐6 (KL‐6) serum levels in patients with anti‐MDA5 antibody‐positive dermatomyositis (anti‐MDA5+ DM) having interstitial lung disease (ILD), especially in the amyopathic DM phenotype. read more here.
Keywords: positive dermatomyositis; anti mda5; antibody positive; interstitial lung ... See more keywords
Anti-MDA5 antibody-positive rapidly progressive interstitial pneumonia without cutaneous manifestations
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DOI: 10.1016/j.rmcr.2019.01.012
Abstract: A 47-year-old man was referred to our hospital with a 1-month history of fever and dyspnea after inhalation of insecticide in a confined space. We diagnosed rapidly progressive interstitial pneumonia. High-dose methylprednisolone, tacrolimus, and intermittent… read more here.
Keywords: anti mda5; rapidly progressive; antibody positive; mda5 antibody ... See more keywords
The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients.
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DOI: 10.1093/rheumatology/key386
Abstract: Objectives Based on the antibody profiles of inflammatory myositis patients, we investigated the type 1 IFN (T1-IFN) signature in serum and DM skin to determine the relationship between T1-IFN and vasculopathy in anti-melanoma differentiation-associated 5… read more here.
Keywords: ifn; antibody; group; antibody positive ... See more keywords
Prognosis of spontaneous pneumomediastinum occurring in dermatomyositis or polymyositis patients with interstitial lung disease according to antimelanoma differentiation-associated gene 5 antibody status: a retrospective cohort study
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DOI: 10.1136/rmdopen-2022-002770
Abstract: Objectives Spontaneous pneumomediastinum (SPNM) historically has been considered a poor prognostic factor in dermatomyositis/polymyositis patients complicated with interstitial lung disease (ILD). However, there is a lack of actual data regarding the association between SPNM occurrence… read more here.
Keywords: anti mda5; dermatomyositis polymyositis; spnm group; mda5 antibody ... See more keywords
Efficacy and safety of dose escalation of tofacitinib in refractory anti-MDA5 antibody-positive dermatomyositis
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DOI: 10.1136/rmdopen-2022-002795
Abstract: Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM) is frequently complicated with rapidly progressive-interstitial lung disease (RP-ILD). The prognosis of MDA5-DM with RP-ILD is mostly poor despite intensive treatment with a combination of high-dose glucocorticoids… read more here.
Keywords: escalation tofacitinib; dose escalation; mda5; mda5 antibody ... See more keywords
Anti-MDA5 Antibody-Positive Dermatomyositis Presenting with Cellulitis-Like Erythema on the Mandible as an Initial Symptom
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DOI: 10.1159/000488077
Abstract: Panniculitis is an uncommon skin eruption observed in patients with dermatomyositis (DM)/clinically amyopathic dermatomyositis (CADM), especially in anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive DM. We present here a 51-year-old Japanese woman with an anti-MDA5 antibody-positive… read more here.
Keywords: antibody positive; mda5 antibody; anti mda5; cellulitis like ... See more keywords
Anti-MDA5 antibody-positive bullous dermatomyositis with thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2018.3287
Abstract: EJD, vol. 28, n◦ 3, May-June 2018 to be heterogeneous and complex. The precise characterisation of autoantibodies may shed light on the pathogenesis of AHA [7]. Severe forms of psoriasis are associated with a decreased… read more here.
Keywords: anti mda5; positive bullous; antibody positive; mda5 antibody ... See more keywords
Assessment of anti-MDA5 antibody as a diagnostic biomarker in patients with dermatomyositis-associated interstitial lung disease or rapidly progressive interstitial lung disease
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DOI: 10.18632/oncotarget.19050
Abstract: Anti-melanoma differentiation-associated protein 5 (MDA5) antibody have been found in dermatomyositis (DM)-associated interstitial lung disease (DM-ILD) and DM-associated rapidly progressive ILD (DM-RPILD). Due to the conflicting results regarding the association between anti-MDA5 antibody and DM-ILD… read more here.
Keywords: anti mda5; antibody; lung disease; interstitial lung ... See more keywords
Interstitial Lung Disease with Anti-melanoma Differentiation-associated Protein 5 Antibody: Rapidly Progressive Perilobular Opacity
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DOI: 10.2169/internalmedicine.2328-18
Abstract: Objective Rapidly progressive interstitial lung disease (RP-ILD) with anti-melanoma differentiation-associated protein 5 (MDA5) antibody potentially presents with a fatal clinical course and requires early intensive treatment. Recently, perilobular opacity was reported to pathologically correspond to… read more here.
Keywords: perilobular opacity; rapidly progressive; antibody; mda5 antibody ... See more keywords
ECG Changes Through Immunosuppressive Therapy Indicate Cardiac Abnormality in Anti-MDA5 Antibody-Positive Clinically Amyopathic Dermatomyositis
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DOI: 10.3389/fimmu.2021.765140
Abstract: Anti-melanoma differentiation-associated gene 5 (MDA5) antibody, a dermatomyositis (DM)-specific antibody, is strongly associated with interstitial lung disease (ILD). Patients with idiopathic inflammatory myopathy (IIM) who are anti-MDA5 antibody positive [anti-MDA5 (+)] often experience chest symptoms… read more here.
Keywords: group; mda5; phase; mda5 antibody ... See more keywords
Fulminant Course of Neuromyelitis Optica in a Patient With Anti-MDA5 Antibody-Positive Dermatomyositis: A Case Report
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DOI: 10.3389/fmed.2020.576436
Abstract: Anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody is a myositis-specific marker detected in clinically amyopathic dermatomyositis (DM). DM with anti-MDA5 antibody can be accompanied by rapidly progressive interstitial lung disease (RP-ILD) and other autoimmune disorders. Until… read more here.
Keywords: mda5 antibody; anti; anti mda5; patient ... See more keywords