MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance
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DOI: 10.1172/jci.insight.157929
Abstract: Type 1 diabetes (T1D) is an autoimmune disease resulting in pancreatic β cell destruction. Coxsackievirus B3 (CVB3) infection and melanoma differentiation-associated protein 5–dependent (MDA5-dependent) antiviral responses are linked with T1D development. Mutations within IFIH1, coding… read more here.
Keywords: dependent responses; nod mice; t1d; mice ... See more keywords