Serum YKL-40 level is associated with severity of interstitial lung disease and poor prognosis in dermatomyositis with anti-MDA5 antibody
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DOI: 10.1007/s10067-019-04457-w
Abstract: ObjectiveWe aimed to investigate the clinical value of checking serum chitinase-3-like-1 protein (YKL-40) levels in anti-MDA5 antibody-positive dermatomyositis (anti-MDA5+DM) patients.MethodsOne hundred and five consecutive anti-MDA5+DM patients and 44 healthy controls were enrolled in this study.… read more here.
Keywords: anti mda5; serum ykl; interstitial lung; mda5 patients ... See more keywords
Different Multivariable Risk Factors for Rapid Progressive Interstitial Lung Disease in Anti-MDA5 Positive Dermatomyositis and Anti-Synthetase Syndrome
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DOI: 10.3389/fimmu.2022.845988
Abstract: Background Interstitial lung disease (ILD) is frequently observed in anti-melanoma differentiation-associated protein 5 (MDA5) antibody positive dermatomyositis (DM) and anti-synthetase syndrome (ASS), where they often develop a rapidly progressive ILD (RP-ILD) leading to poor prognosis.… read more here.
Keywords: ass patients; risk factors; risk; mda5 patients ... See more keywords