Articles with "mdd patients" as a keyword



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Psychotic symptoms in first-episode and drug naïve patients with major depressive disorder: Prevalence and related clinical factors.

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Published in 2020 at "Depression and anxiety"

DOI: 10.1002/da.23026

Abstract: BACKGROUND Many patients with major depressive disorder (MDD) have been found to have psychotic symptoms. However, few studies have reported the prevalence of comorbid psychotic symptoms in first-episode drug naïve (FEDN) MDD patients. This study… read more here.

Keywords: mdd patients; anxiety; first episode; prevalence ... See more keywords
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Inflammatory cytokines derived from peripheral blood contribute to the modified electroconvulsive therapy-induced cognitive deficits in major depressive disorder

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Published in 2020 at "European Archives of Psychiatry and Clinical Neuroscience"

DOI: 10.1007/s00406-020-01128-9

Abstract: Little is known about the pathophysiology of memory deficits in patients with major depressive disorder (MDD) treated with modified electroconvulsive therapy (MECT). This study examined the profiles of cytokines, the memory function, and their association… read more here.

Keywords: mdd patients; depressive disorder; mdd; major depressive ... See more keywords
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Concurrent alterations of white matter microstructure and functional activities in medication-free major depressive disorder

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Published in 2020 at "Brain Imaging and Behavior"

DOI: 10.1007/s11682-020-00411-6

Abstract: Although numerous studies have revealed the structural and functional alterations in major depressive disorder (MDD) using unimodal diffusion magnetic resonance imaging (MRI) or functional MRI, however, the potential associations between changed microstructure and corresponding functional… read more here.

Keywords: functional activities; mdd patients; depressive disorder; major depressive ... See more keywords
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Gambling in patients with major depressive disorder is associated with an elevated risk of Suicide: Insights from 12-years of Nationwide inpatient sample data.

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Published in 2021 at "Addictive behaviors"

DOI: 10.1016/j.addbeh.2021.106872

Abstract: BACKGROUND There is a frequent occurrence of gambling disorder (GD) in patients with major depressive disorder (MDD). Psychiatric comorbidities can present more severely in patients diagnosed with pathological gambling. There is limited information on symptom… read more here.

Keywords: mdd patients; risk; diagnosis; disorder ... See more keywords
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Common and Specific Abnormalities in Cortical Thickness in Patients with Major Depressive and Bipolar Disorders

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Published in 2017 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2017.01.010

Abstract: Major depressive disorder (MDD) and bipolar disorder (BD) are severe psychiatric diseases with overlapping symptomatology. Although previous studies reported abnormal brain structures in MDD or BD patients, the disorder-specific underlying neural mechanisms remain poorly understood.… read more here.

Keywords: mdd patients; healthy controls; major depressive; brain ... See more keywords
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Global arginine bioavailability ratio is decreased in patients with major depressive disorder.

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Published in 2018 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2017.12.030

Abstract: BACKGROUND Major depressive disorder (MDD) is characterized by increased oxidative and nitrosative stress. We compared nitric oxide metabolism, i.e., the global arginine bioavailability ratio (GABR) and related serum amino acids, between MDD patients and non-depressed… read more here.

Keywords: mdd patients; mdd; arginine; non remitted ... See more keywords
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Comparison of shape alterations of the thalamus and caudate nucleus between drug-naïve major depressive disorder patients and healthy controls.

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Published in 2020 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2020.01.011

Abstract: BACKGROUND Although structural alterations have been reported in patients with major depressive disorder (MDD), very few studies have compared the shape alterations of the subcortical regions between drug-naïve MDD patients and healthy controls (HCs). Therefore,… read more here.

Keywords: mdd patients; mdd; drug; drug mdd ... See more keywords
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Longitudinal changes of amplitude of low-frequency fluctuations in MDD patients: A 6-month follow-up resting-state functional magnetic resonance imaging study.

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Published in 2020 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2020.07.067

Abstract: OBJECTIVE The aim of this study includes: (1) using resting-state functional magnetic resonance imaging (rsfMRI) to explore the aberrant brain regional spontaneous brain activities in acute major depressive disorder (MDD) patients; (2) to determine whether… read more here.

Keywords: mdd patients; mdd; group; resting state ... See more keywords
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Increased ratio of mature BDNF to precursor-BDNF in patients with major depressive disorder with severe anhedonia.

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Published in 2020 at "Journal of psychiatric research"

DOI: 10.1016/j.jpsychires.2020.05.010

Abstract: BACKGROUND Although studies have shown that severe anhedonia in patients with major depressive disorder (MDD) is associated with poor treatment outcomes, the biological mechanism of this feature is unclear. The aim of this study was… read more here.

Keywords: mdd patients; mature bdnf; precursor bdnf; severe anhedonia ... See more keywords
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The role of circulating blood microRNA-374 and microRNA-10 levels in the pathogenesis and therapeutic mechanisms of major depressive disorder

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Published in 2021 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2021.136184

Abstract: Compelling recent evidence suggests that microRNAs (miRNAs) regulate specific mRNA transcripts at the transcriptomic level and coordinately influence complex regulatory networks, which may play a crucial role in the pathogenesis of major depressive disorder (MDD)… read more here.

Keywords: mdd patients; depressive disorder; mdd; major depressive ... See more keywords
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Electroretinographic anomalies in medicated and drug free patients with major depression: Tagging the developmental roots of major psychiatric disorders

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Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"

DOI: 10.1016/j.pnpbp.2016.12.002

Abstract: ABSTRACT The retina is tagged as an approachable part of the brain due to its common embryonic origin and appears as a promising site of investigation for psychiatric disorders. Retinal function is assessed best with… read more here.

Keywords: mdd patients; psychiatric disorders; free patients; drug ... See more keywords