Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.
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DOI: 10.1021/acs.jmedchem.7b01231
Abstract: Previously, we reported a hypoxia-inducible factor (HIF)-1 inhibitor LW6 containing an (aryloxyacetylamino)benzoic acid moiety inhibits malate dehydrogenase 2 (MDH2) using a chemical biology approach. Structure-activity relationship studies on a series of (aryloxyacetylamino)benzoic acids identified selective… read more here.
Keywords: mdh2; inhibitor; malate dehydrogenase; cancer metabolism ... See more keywords
Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots.
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DOI: 10.12688/f1000research.13396.1
Abstract: Malate dehydrogenases (Mdhs) reversibly convert malate to oxaloacetate and serve as important enzymes in several metabolic pathways. In the yeast Saccharomyces cerevisiae there are three Mdh isozymes, localized to different compartments in the cell. In… read more here.
Keywords: validation yeast; mdh2; dehydrogenase mdh2; mdh2 antibody ... See more keywords
Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots
Sign Up to like & getrecommendations! Published in 2018 at "F1000Research"
DOI: 10.12688/f1000research.13396.2
Abstract: Malate dehydrogenases (Mdhs) reversibly convert malate to oxaloacetate and serve as important enzymes in several metabolic pathways. In the yeast Saccharomyces cerevisiae there are three Mdh isozymes, localized to different compartments in the cell. In… read more here.
Keywords: validation yeast; mdh2; dehydrogenase mdh2; mdh2 antibody ... See more keywords