MDM2-Based Proteolysis-Targeting Chimeras (PROTACs): An Innovative Drug Strategy for Cancer Treatment
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DOI: 10.3390/ijms231911068
Abstract: Proteolysis-targeting chimeras (PROTACs) are molecules that selectively degrade a protein of interest (POI). The incorporation of ligands that recruit mouse double minute 2 (MDM2) into PROTACs, forming the so-called MDM2-based PROTACs, has shown promise in… read more here.
Keywords: chimeras protacs; mdm2 based; proteolysis targeting; cancer treatment ... See more keywords