Articles with "mdm2 cdk4" as a keyword



Low-Grade Uterine Adenosarcoma with Overexpression of MDM2 and CDK4 by Immunohistochemistry: A Case Report and Literature Review

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Published in 2024 at "Case Reports in Oncology"

DOI: 10.1159/000541823

Abstract: Abstract Introduction Uterine adenosarcoma (UA) is a rare malignant mesenchymal neoplasm characterized by benign epithelial and malignant stromal components. Comprehensive genomic profiling has identified a high frequency of murine double-minute type 2 (MDM2) and cyclin-dependent… read more here.

Keywords: uterine adenosarcoma; mdm2 cdk4; cdk4; immunohistochemistry ... See more keywords

Castleman Disease with MDM2/CDK4 Protein Expression: a Potential Mimic of Inflammatory Variant of Liposarcoma with Significant Consequences

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Published in 2022 at "International Journal of Surgical Pathology"

DOI: 10.1177/10668969221080083

Abstract: Castleman disease is a rare benign lymphoproliferative disorder that includes a spectrum of distinct histopathological entities. The differential diagnosis of Castleman disease is broad and includes lymphomas, HIV-related lymphadenopathy, autoimmune disorders, and inflammatory liposarcoma. When… read more here.

Keywords: disease; inflammatory variant; castleman disease; mdm2 cdk4 ... See more keywords

Juvenile trabecular ossifying fibroma: Immunohistochemical expression of MDM2, CDK4 and p53 compared to conventional ossifying fibroma

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Published in 2022 at "Journal of Clinical and Experimental Dentistry"

DOI: 10.4317/jced.59116

Abstract: Background Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion of the craniofacial skeleton; compared to conventional ossifying fibroma (OF), JOF is characterized by local aggressiveness and propensity for recurrence. The biologic basis for… read more here.

Keywords: mdm2 cdk4; expression; ossifying fibroma; jof ... See more keywords