Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2‐Mediated Degradation of p53
Sign Up to like & getrecommendations! Published in 2017 at "STEM CELLS"
DOI: 10.1002/stem.2620
Abstract: Bre is a conserved cellular protein expressed in various tissues. Its major function includes DNA damage repair and anti‐apoptosis. Recent studies indicate that Bre is potentially involved in stem cell differentiation although pathophysiological significance along… read more here.
Keywords: mdm2 mediated; bre; bone; differentiation ... See more keywords
Mdm2-mediated ubiquitination of β-arrestin2 in the nucleus occurs in a Gβγ- and clathrin-dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114049
Abstract: The fate and activity of β-arrestin2, a key player in the regulation of desensitization and endocytosis of G protein-coupled receptors (GPCRs), are regulated by mouse double minute 2 homolog (Mdm2)-mediated ubiquitination. However, details of the… read more here.
Keywords: arrestin2; mdm2 mediated; mdm2; clathrin dependent ... See more keywords