Articles with "mdm2 pathway" as a keyword



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Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope.

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Published in 2020 at "Cancer letters"

DOI: 10.1016/j.canlet.2020.09.023

Abstract: Despite being the subject of extensive research and clinical trials, neuroblastoma remains a major therapeutic challenge in pediatric oncology. The p53 protein is a central safeguard that protects cells against genome instability and malignant transformation.… read more here.

Keywords: p53; p53 mdm2; mdm2 pathway; pathway neuroblastoma ... See more keywords