Structural studies of antitumor compounds that target the RING domain of MDM2
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DOI: 10.1002/pro.4367
Abstract: Mouse double minute 2 homolog (MDM2) is an E3 ubiquitin‐protein ligase that is involved in the transfer of ubiquitin to p53 and other protein substrates. The expression of MDM2 is elevated in cancer cells and… read more here.
Keywords: structural studies; mdm2; mdm2 ring; ring domain ... See more keywords