Abstract 708: Characterization of MDNA132, an IL-13 decoy receptor selective superkine for targeted delivery of immunotherapies to the tumor microenvironment
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DOI: 10.1158/1538-7445.am2023-708
Abstract: Background: Interleukin-13 (IL-13) exhibits high affinity for the IL-13 decoy receptor (IL13Rα2) but retains binding to IL13α1, a component of the functional Type II IL4R complex (IL4Rα/IL13Rα1) that elicits a Th2 immune response. IL13Rα2 expression… read more here.
Keywords: il13r; anti pd1; mdna132; decoy receptor ... See more keywords