How Structure–Function Relationships of 1,4‐Naphthoquinones Combat Antimicrobial Resistance in Multidrug‐Resistant (MDR) Pathogens
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DOI: 10.1002/cmdc.202200471
Abstract: Antimicrobial resistance (AMR) is one of the top ten health‐related threats worldwide. Among several antimicrobial agents, naphthoquinones (NQs) of plant/chemical origin possess enormous structural and functional diversity and are effective against multidrug‐resistant (MDR) pathogens. 1,4‐NQs… read more here.
Keywords: structure; mdr; mdr pathogens; multidrug resistant ... See more keywords
Heterocyclic Diaryliodonium-Based Inhibitors of Carbapenem-Resistant Acinetobacter baumannii
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DOI: 10.1128/spectrum.04773-22
Abstract: Discovery of novel antibiotics targeting multidrug-resistant (MDR) pathogens such as A. baumannii is an urgent, unmet medical need. Our work has highlighted the potential of this unique scaffold to annihilate MDR A. baumannii alone and… read more here.
Keywords: carbapenem resistant; resistant acinetobacter; mdr pathogens; acinetobacter baumannii ... See more keywords
MDR Pathogens Organisms as Risk Factor of Mortality in Secondary Pulmonary Bacterial Infections Among COVID-19 Patients: Observational Studies in Two Referral Hospitals in West Java, Indonesia
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DOI: 10.2147/ijgm.s359959
Abstract: Purpose The coronavirus disease (COVID-19) outbreak has created a global health crisis. Secondary pulmonary bacterial infection is a COVID-19 complication, increasing morbidity and mortality. This study aimed to determine the pathogens, antibiotic susceptibility patterns, and… read more here.
Keywords: covid patients; mdr pathogens; mortality; risk ... See more keywords
A State-of-Art Review on Multi-Drug Resistant Pathogens in Foods of Animal Origin: Risk Factors and Mitigation Strategies
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DOI: 10.3389/fmicb.2019.02091
Abstract: Most of the foodborne microbial diseases are linked to foods of animal origin such as milk, meat, and poultry. Nowadays, the presence of multi-drug resistant (MDR) pathogens in foods is becoming an increasingly public health… read more here.
Keywords: mdr pathogens; multi drug; animal origin; food ... See more keywords
Bacteriological profile of ventilator-associated pneumonia in a tertiary care hospital
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DOI: 10.4103/ijpm.ijpm_487_16
Abstract: Background: Ventilator-associated pneumonia (VAP) is the most frequent intensive care unit (ICU)-acquired infection. The etiology of VAP and their antimicrobial susceptibility pattern varies with different patient populations and types of ICUs. Materials and Methods: An… read more here.
Keywords: mdr pathogens; associated pneumonia; care hospital; ventilator associated ... See more keywords