In silico epitope identification of unique multidrug resistance proteins from Salmonella Typhi for vaccine development
Sign Up to like & getrecommendations! Published in 2019 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2018.11.020
Abstract: Typhoid fever is a multisystemic illness caused by Salmonella enterica serovars Typhi and is resistant to most antibiotics and drugs. The resistance is conferred through multidrug resistance (MDR) proteins, which efflux most antibiotics and other… read more here.
Keywords: mdr proteins; tolc; cell epitopes; multidrug resistance ... See more keywords
The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
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DOI: 10.3390/membranes13060568
Abstract: Multidrug resistance (MDR) proteins belonging to the ATP-Binding Cassette (ABC) transporter group play a crucial role in the export of cytotoxic drugs across cell membranes. These proteins are particularly fascinating due to their ability to… read more here.
Keywords: alternating access; multidrug resistance; access mechanism; mdr proteins ... See more keywords