Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers.
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DOI: 10.1021/acs.jnatprod.8b00326
Abstract: The phytochemical study of Euphorbia pedroi led to the isolation of a new tetracyclic triterpenoid with an unusual spiro scaffold, spiropedroxodiol (1), along with seven known terpenoids (2-8). Aiming at obtaining compounds with improved multidrug-resistance… read more here.
Keywords: terpenoids euphorbia; mdr reversal; euphorbia pedroi; multidrug resistance ... See more keywords
Pentasaccharide resin glycosides with multidrug resistance reversal activities from the seeds of Pharbitis nil
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DOI: 10.1039/c7ra09026a
Abstract: Resin glycosides are novel P-glycoprotein inhibitors. In order to evaluate their multidrug resistance (MDR) reversal activities, we isolated seven new resin glycosides, pharbitins A–G (1–7) from the seeds of Pharbitis nil. Their chemical structures were… read more here.
Keywords: multidrug resistance; mdr reversal; resin glycosides; reversal activities ... See more keywords
Study on the Chemical Composition and Multidrug Resistance Reversal Activity of Euphorbia uralensis (Euphorbiaceae)
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DOI: 10.3390/ijms26010412
Abstract: Euphorbia uralensis belongs to the family Euphorbiaceae and is widely distributed in northern Xinjiang, making it a characteristic plant of the region in Xinjiang, China. The chemical composition and biological activity of Euphorbia uralensis have… read more here.
Keywords: mdr reversal; euphorbia uralensis; reversal activity; activity ... See more keywords