Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers.
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DOI: 10.1021/acs.jnatprod.8b00326
Abstract: The phytochemical study of Euphorbia pedroi led to the isolation of a new tetracyclic triterpenoid with an unusual spiro scaffold, spiropedroxodiol (1), along with seven known terpenoids (2-8). Aiming at obtaining compounds with improved multidrug-resistance… read more here.
Keywords: terpenoids euphorbia; mdr reversal; euphorbia pedroi; multidrug resistance ... See more keywords
Pentasaccharide resin glycosides with multidrug resistance reversal activities from the seeds of Pharbitis nil
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DOI: 10.1039/c7ra09026a
Abstract: Resin glycosides are novel P-glycoprotein inhibitors. In order to evaluate their multidrug resistance (MDR) reversal activities, we isolated seven new resin glycosides, pharbitins A–G (1–7) from the seeds of Pharbitis nil. Their chemical structures were… read more here.
Keywords: multidrug resistance; mdr reversal; resin glycosides; reversal activities ... See more keywords