Emergence and spread in Taiwan of multidrug-resistant serotypes of nontyphoidal Salmonella
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DOI: 10.1007/s15010-021-01736-0
Abstract: Purpose Antimicrobial resistance of nontyphoidal Salmonella (NTS) is a threat to public health worldwide. Methods A study on longitudinally collected NTS isolates from a medical center in Taiwan from 2011 to 2019 was undertaken. The… read more here.
Keywords: xdr nts; mdr; nontyphoidal salmonella; multidrug ... See more keywords
Interim Effectiveness and Safety Comparison of Bedaquiline-Containing Regimens for Treatment of Diabetic Versus Non-Diabetic MDR/XDR-TB Patients in China: A Multicenter Retrospective Cohort Study
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DOI: 10.1007/s40121-021-00396-9
Abstract: Introduction Diabetes mellitus (DM), a common tuberculosis (TB) comorbidity, is associated with delayed bacillary clearance during anti-TB treatment and unfavorable outcomes. Bedaquiline (BDQ), when used as part of multidrug regimen for multidrug-resistant/extensively drug-resistant tuberculosis (MDR/XDR-TB),… read more here.
Keywords: week; treatment; culture conversion; study ... See more keywords
Pseudomonas aeruginosa epidemic high-risk clones and their association with horizontally-acquired β-lactamases: 2020 update.
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DOI: 10.1016/j.ijantimicag.2020.106196
Abstract: Pseudomonas aeruginosa global clones associated with multidrug resistant (MDR) or extensively drug resistant (XDR) phenotypes, denominated high-risk clones, are a growing threat in hospitals world-wide. Here we provide a 2020 update of nosocomial MDR/XDR high… read more here.
Keywords: mdr xdr; high risk; risk; risk clones ... See more keywords
Comparative efficacy and safety of treatment options for MDR and XDR Acinetobacter baumannii infections: a systematic review and network meta-analysis
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DOI: 10.1093/jac/dkx368
Abstract: Objectives To comprehensively compare and rank the efficacy and safety of available treatment options for patients with MDR and XDR Acinetobacter baumannii (AB) infection. Methods We searched PubMed, Embase and the Cochrane register of trials… read more here.
Keywords: colistin; treatment; treatment options; safety ... See more keywords
Multi and extensively drug-resistant pulmonary tuberculosis: advances in diagnosis and management
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DOI: 10.1097/mcp.0000000000000477
Abstract: Purpose of review Multidrug-resistant (MDR) tuberculosis (TB) and extensively drug-resistant (XDR)-TB epidemics are key obstacles towards TB control and elimination. Recent findings Diagnosis of MDR/XDR-TB is difficult and requires several weeks. New diagnostic tools are… read more here.
Keywords: treatment; drug resistant; extensively drug; mdr xdr ... See more keywords
Recent controversies about MDR and XDR‐TB: Global implementation of the WHO shorter MDR‐TB regimen and bedaquiline for all with MDR‐TB?
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DOI: 10.1111/resp.13143
Abstract: Tuberculosis (TB) is now the biggest infectious disease killer worldwide. Although the estimated incidence of TB has marginally declined over several years, it is out of control in some regions including in Africa. The advent… read more here.
Keywords: mdr; drug; drug resistant; mdr xdr ... See more keywords
Laboratory-based study of drug resistance and genotypic profile of multidrug-resistant tuberculosis isolates in Salvador, Bahia, Brazil
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DOI: 10.1590/0037-8682-0013-2022
Abstract: Abstract Background: Surveillance of multidrug resistant/extensively drug-resistant tuberculosis (MDR/XDR-TB) is essential to guide disease dissemination control measures. Brazil contributes to a significant fraction of tuberculosis (TB) cases worldwide, but only few reports addressed MDR/XDR-TB in… read more here.
Keywords: mdr xdr; resistant tuberculosis; resistance; multidrug resistant ... See more keywords
Epidemiology, susceptibility, and risk factors for acquisition of MDR/XDR Gram-negative bacteria among kidney transplant recipients with urinary tract infections
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DOI: 10.2147/idr.s163979
Abstract: Background Multiple drug resistant/extensively drug resistant (MDR/XDR) Gram-negative urinary tract infections (UTIs) represent a growing threat to kidney transplant recipients. This retrospective study aimed to assess the incidence and microbiological profile of MDR/XDR Gram-negative UTIs,… read more here.
Keywords: gram negative; mdr xdr; xdr gram; xdr ... See more keywords
The Anti-Mycobacterial Activity Of Ag, ZnO, And Ag- ZnO Nanoparticles Against MDR- And XDR-Mycobacterium tuberculosis
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DOI: 10.2147/idr.s221408
Abstract: Background Nowadays, tuberculosis (TB) is one of the top ten leading causes of mortality worldwide. The emergence of multidrug-resistant (MDR) – and extensively drug-resistant (XDR) – Mycobacterium tuberculosis (M. tuberculosis) is identified as one of… read more here.
Keywords: xdr mycobacterium; mdr xdr; tuberculosis; zno zno ... See more keywords
Linezolid-Associated Neuropathy in Patients with MDR/XDR Tuberculosis in Shenzhen, China
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DOI: 10.2147/idr.s365371
Abstract: Objective Linezolid is one of the key drugs for the treatment of multidrug-resistant/extensively drug-resistant tuberculosis (MDR/XDR-TB). We aimed to describe the incorporation of the Michigan Neuropathy Screening Instrument (MNSI) and serum trough concentration as screening… read more here.
Keywords: neuropathy patients; tuberculosis; mdr xdr; serum trough ... See more keywords
Evidence-Based Treatment of Pseudomonas aeruginosa Infections: A Critical Reappraisal
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DOI: 10.3390/antibiotics12020399
Abstract: Multidrug-resistant (MDR)/extensively drug-resistant (XDR) Pseudomonas aeruginosa is emerging as a major threat related to adverse patient outcomes. The goal of this review is to describe evidence-based empiric and targeted treatment regimens that can be exploited… read more here.
Keywords: pseudomonas aeruginosa; mdr xdr; resistance; treatment ... See more keywords