Fast and simple detection methods for the 4–base pair deletion of canine MDR1/ABCB1 gene by PCR and isothermal amplification
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DOI: 10.1177/1040638716683213
Abstract: Dogs with a 4-bp deletion in the MDR1 (or ABCB1) gene show intolerance to certain drugs routinely used in veterinary medicine, such as ivermectin, vincristine, and doxorubicin. The mutation leads to a dysfunctional P-glycoprotein drug… read more here.
Keywords: mdr1 abcb1; isothermal amplification; deletion; abcb1 gene ... See more keywords