Chemoresistance in Malignant Intracranial Tumors: Longer Survival with Negative MDR1 Expression.
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DOI: 10.5137/1019-5149.jtn.29819-20.3
Abstract: AIM One challenge of malignant intracranial tumor (ICT) management is chemoresistance. Glutathione S-transferase (GST) and cytochrome p450 (CYP) are featured medicine degradation agents. MDR1, an outflow carrier, reduces drug accumulation into the multidrug-resistant cells. Our… read more here.
Keywords: expression; overall survival; malignant intracranial; negative mdr1 ... See more keywords