Articles with "mdr1 polymorphisms" as a keyword



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Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms

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Published in 2018 at "Cancer Chemotherapy and Pharmacology"

DOI: 10.1007/s00280-018-3751-0

Abstract: PurposeThis study investigated correlations of the clinical outcomes of oral metronomic vinorelbine (VNR) with VNR pharmacokinetics and MDR1 polymorphisms.MethodsEighty-two patients with metastatic non-small cell lung cancer (NSCLC) unfit for standard chemotherapy were treated with VNR… read more here.

Keywords: outcomes oral; clinical outcomes; mdr1 polymorphisms; toxicity ... See more keywords