Enumerating bone marrow blasts from nonerythroid cellularity improves outcome prediction in myelodysplastic syndromes and permits a better definition of the intermediate risk category of the Revised International Prognostic Scoring System (IPSS‐R)
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DOI: 10.1002/ajh.24732
Abstract: The Revised International Prognostic Scoring System (IPSS‐R) has been recognized as the score with the best outcome prediction capability in MDS, but this brought new concerns about the accurate prognostication of patients classified into the… read more here.
Keywords: category; risk; outcome prediction; mds ... See more keywords
Response to Dr. Bain's comment on our review article: Pure Erythroid Leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of hematology"
DOI: 10.1002/ajh.24862
Abstract: Word Count: N/A Main Text Word Count: 339 Number of References: 3 # Correspondence: Josehp D. Khoury, MD Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston, Texas 77030 Phone: 713-745-2387 Fax:… read more here.
Keywords: aml mrc; article; pel; mds ... See more keywords
Hypomethylating agents in combination with histone deacetylase inhibitors in higher risk myelodysplastic syndromes: Is there a light at the end of the tunnel?
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DOI: 10.1002/cncr.30532
Abstract: Myelodysplastic syndromes (MDS) are genetically, biologically, and clinically very heterogeneous. Although allogeneic stem cell transplantation (alloSCT) remains the only intervention with a potential for cure, less than 5% of patients undergo transplantation because of age… read more here.
Keywords: myelodysplastic syndromes; histone deacetylase; higher risk; hypomethylating agents ... See more keywords
Distributed and multicore QuBiLS‐MIDAS software v2.0: Computing chiral, fuzzy, weighted and truncated geometrical molecular descriptors based on tensor algebra
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DOI: 10.1002/jcc.26167
Abstract: Advances to the distributed, multi‐core and fully cross‐platform QuBiLS‐MIDAS software v2.0 (http://tomocomd.com/qubils-midas) are reported in this article since the v1.0 release. The QuBiLS‐MIDAS software is the only one that computes atom‐pair and alignment‐free geometrical MDs… read more here.
Keywords: information; midas mds; midas software; qubils midas ... See more keywords
Bone marrow free immune checkpoints as a potential biomarker for differential diagnosis of acquired bone marrow failures
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DOI: 10.1002/jcla.24677
Abstract: Clinically, to make a definite diagnosis of aplastic anemia (AA), idiopathic cytopenia of undetermined significance (ICUS) or myelodysplastic syndrome (MDS), they should be distinguished from each other. AA and ICUS have some incidence to transform… read more here.
Keywords: mds; bone marrow; marrow; diagnosis ... See more keywords
Development and Characterization of PLGA-Based Multistage Delivery System for Enhanced Payload Delivery to Targeted Vascular Endothelium.
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DOI: 10.1002/mabi.202000377
Abstract: Vascular-targeted drug delivery remains an attractive platform for therapeutic and diagnostic interventions in human diseases. This work focuses on the development of a poly-lactic-co-glycolic-acid (PLGA)-based multistage delivery system (MDS). MDS consists of two stages: a… read more here.
Keywords: based multistage; delivery; plga based; mds ... See more keywords
Movement Disorders and Musculoskeletal System: A Reciprocal Relationship
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DOI: 10.1002/mdc3.13390
Abstract: The association of movement disorders (MDs) with musculoskeletal (MSK) disorders is observed in two principal scenarios. First, MDs patients may present with MSK issues. This phenomenon is primarily observed in parkinsonian syndromes, but may also… read more here.
Keywords: movement disorders; mds; system; msk disorders ... See more keywords
Clinical, biological, and prognostic implications of SF3B1 co-occurrence mutations in very low/low- and intermediate-risk MDS patients
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DOI: 10.1007/s00277-020-04360-4
Abstract: SF3B1 is a highly mutated gene in myelodysplastic syndrome (MDS) patients, related to a specific subtype and parameters of good prognosis in MDS without excess blasts. More than 40% of MDS patients carry at least… read more here.
Keywords: biological prognostic; clinical biological; mds patients; mds ... See more keywords
Therapy-related myeloid neoplasms following treatment for multiple myeloma—a single center analysis
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DOI: 10.1007/s00277-022-04775-1
Abstract: Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) can be late complications following mutagenic treatment. Limited data is available on the outcome of patients developing therapy-related MDS and AML after treatment for multiple myeloma (MM).… read more here.
Keywords: therapy related; mds; myeloma; treatment multiple ... See more keywords
How the structure and form of vegetation in a black locust (Robinia pseudoacacia L.) silvopastoral system influences tree growth, forage mass and its nutrient content
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DOI: 10.1007/s10457-020-00552-z
Abstract: By using two thinning intensity regimes on a dense 16-year-old black locust (Robinia pseudoacacia L.) stand, two silvopastures were created: a medium density silvopasture (MDS) with 60% mean crown cover and a low density silvopasture… read more here.
Keywords: locust; mds; herbage; forage ... See more keywords
Molecular Data and the IPSS-R: How Mutational Burden Can Affect Prognostication in MDS
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DOI: 10.1007/s11899-017-0407-9
Abstract: Purpose of ReviewThe purpose of this study is to review established prognostic models in myelodysplastic syndromes (MDS) and describe how molecular data can be used to improve patient risk stratification.Recent FindingsSomatic mutations are common in… read more here.
Keywords: risk; molecular data; data ipss; risk stratification ... See more keywords