Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2016.516
Abstract: Hepatocellular carcinoma (HCC) is linked to inflammation and immunosuppression. Chemerin is highly expressed in the liver and implicated in the regulation of inflammation. However, the role of chemerin in HCC remains unclear. In this study,… read more here.
Keywords: hepatocellular carcinoma; csf; mdsc accumulation; chemerin ... See more keywords
Abstract 2956: Chemical library screen identifies compounds that target S100A8/S100A9 complex and MDSC accumulation
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-2956
Abstract: We previously demonstrated that MDSC subsets accumulated in primary tumor and distant organs regulate tumor plasticity. The mouse transcriptome analysis of in vitro co-cultures and samples from syngeneic mouse model revealed that granulocytic subset of… read more here.
Keywords: cancer; tumor; mdsc accumulation; s100a8 s100a9 ... See more keywords