Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma
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DOI: 10.1007/s00262-019-02414-9
Abstract: Hepatic stellate cells (HSCs) are important stromal cells and pivotal mediators involved in the pathogenesis and immunosuppression of hepatocellular carcinoma (HCC). The liver has been demonstrated to be a site for accumulation of tumor-induced myeloid-derived… read more here.
Keywords: sdf cxcr4; hcc; cxcr4 axis; mdsc migration ... See more keywords