NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02615-7
Abstract: A major factor impeding the success of numerous therapeutic approaches in cancer is the immunosuppressive nature of the tumor microenvironment (TME). Hence, methods capable of reverting tumor immunosuppression through depletion or reprogramming of myeloid-derived suppressive… read more here.
Keywords: mdscs tregs; antitumor immunity; nkg2d fusion; depletion ... See more keywords
Exosomes, MDSCs and Tregs: A new frontier for GVHD prevention and treatment
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1143381
Abstract: The development of graft versus host disease (GVHD) represents a long-standing complication of allogeneic hematopoietic cell transplantation (allo-HCT). Different approaches have been used to control the development of GVHD with most relying on variations of… read more here.
Keywords: mdscs tregs; prevention treatment; gvhd prevention; exosomes mdscs ... See more keywords