Anaesthetic efficacy of 4% articaine compared with 2% mepivacaine: a randomized, double-blind, crossover clinical trial.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of oral and maxillofacial surgery"
DOI: 10.1016/j.ijom.2017.11.011
Abstract: The aim of this study was to evaluate the clinical efficacy of 4% articaine (Ar4) compared to 2% mepivacaine (Me2), both in combination with 1:100,000 epinephrine, in a unique soft tissue model. This was a… read more here.
Keywords: randomized double; me2; efficacy articaine; compared mepivacaine ... See more keywords
Different reactivity of cyclooctadiene complexes 3,3-(cod)-8-SMe2-closo-3,1,2-RhC2B9H10 and 1,8-Me2-2,2-(cod)-11-SMe2-2,1,8-closo-RhC2B9H8 toward iodine
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2018.01.025
Abstract: Abstract Reaction of the thallium salt Tl[7,8-Me2-10-SMe2-7,8-nido-C2B9H8] with [(cod)RhCl]2 in THF furnishes new rhodacarborane 1,2-Me2-3,3-(cod)-8-SMe2-3,1,2-closo-RhC2B9H8 (1). The latter undergoes 1,2 → 1,7 carbon atom isomerization upon reflux in o-xylene for 5 h producing complex 1,8-Me2-2,2-(cod)-11-SMe2-2,1,8-closo-RhC2B9H8 (2). Reaction of… read more here.
Keywords: cod sme2; closo; sme2 closo; me2 ... See more keywords
In the Quest for Potent and Selective Malic Enzyme 3 Inhibitors for the Treatment of Pancreatic Ductal Adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00369
Abstract: The genome of pancreatic ductal adenocarcinoma (PDAC) is associated with frequent deletion of the tumor suppressor gene SMAD family member 4 (SMAD4) with collateral deletion of its chromosomal neighbor malic enzyme 2 (ME2). In SMAD4… read more here.
Keywords: malic enzyme; me2; ductal adenocarcinoma; enzyme ... See more keywords
ME2 Promotes Proneural–Mesenchymal Transition and Lipogenesis in Glioblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.715593
Abstract: Malic enzyme 2 (ME2) catalyzes the formation of pyruvate from malic acid and is abnormally expressed in some tumors. However, the exact effects of ME2 on proneural–mesenchymal transition (PMT) and lipogenesis in glioblastoma multiforme (GBM)… read more here.
Keywords: mesenchymal transition; me2; lipogenesis glioblastoma; gbm ... See more keywords
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13040540
Abstract: Cancer metastasis is still a major challenge in clinical cancer treatment. The migration and invasion of cancer cells into surrounding tissues and blood vessels is the primary step in cancer metastasis. However, the underlying mechanism… read more here.
Keywords: cell migration; migration invasion; migration; me2 ... See more keywords
Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14020288
Abstract: ATP-binding cassette transporter A1 (ABCA1) is a key regulator of lipid efflux, and the absence of ABCA1 induces hepatic lipid accumulation, which is one of the major causes of fatty liver. 2-Methoxyestradiol (2-ME2) has been… read more here.
Keywords: abca1 expression; expression; me2; foxo1 ... See more keywords