Catalytic Enantioselective Addition of Me2Zn to Isatins
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DOI: 10.3390/catal7120387
Abstract: Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several chemical transformations were performed with… read more here.
Keywords: catalytic enantioselective; addition; enantioselective addition; me2zn isatins ... See more keywords