Measurements of Mcl-1 protein dependencies using dimerization-specific antibodies as predictive biomarkers for BH-3 mimetic class therapies in AML.
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DOI: 10.1200/jco.2020.38.15_suppl.e19505
Abstract: e19505Background: The anti-apoptotic Bcl-2 family proteins facilitate pro-survival and resistance to anti-cancer therapies. Measuring the function of these proteins has shown utility in predicting ... read more here.
Keywords: dimerization specific; measurements mcl; mcl protein; protein dependencies ... See more keywords