Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry
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DOI: 10.1016/j.neuroimage.2021.118255
Abstract: Highlights • Dopaminergic neurons dominate effective transverse relaxation in nigrosome 1.• Ion beam microscopy reveals highest iron concentrations in dopaminergic neurons.• Developed biophysical model links MRI parameters to cellular iron content.• Ferritin- and neuromelanin-bound iron… read more here.
Keywords: iron content; mri; dopaminergic neurons; iron ... See more keywords